Psychosocial risk factors for depressive disorders in late life

Psychosocial risk factors for depressive disorders in late life
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DOI:
10.1016/s0006-3223(02)01410-5
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发表时间:
2002-08-01
影响因子:
10.6
通讯作者:
Bruce, ML
Bruce, ML
中科院分区:
医学1区
文献类型:
--
作者:
Bruce, ML

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本文综述了有关老年抑郁障碍心理社会危险因素的研究结果。这篇文章大量采用纵向队列研究,对定义明确的、以人群为基础的样本进行研究,并采用诊断措施评估发生或新发抑郁发作的风险。这些研究确定了晚年抑郁障碍的一些重要的心理社会风险因素,包括生活事件和持续的困难;配偶或其他亲人的死亡;医疗疾病和伤害;残疾和功能衰退:以及缺乏社会联系。更多的证据表明,这些心理社会风险因素对抑郁的影响可以通过个人或环境因素来增强或缓冲。尽管许多这些心理社会风险因素在老年人中比年轻人中更普遍,但尚不清楚它们对抑郁风险的影响是否因年龄而不同。回顾了推进老年抑郁症心理社会危险因素研究的方法论挑战,包括与研究设计、样本选择和测量相关的问题。(C)2002年生物精神病学学会。
This article summarizes research findings on psychosocial risk factors for late life depressive disorders. The article draws heavily on longitudinal cohort studies of well defined, population-based samples with diagnostic measures that assess the risk of incident or new-onset depressive episodes. These studies have identified a number of significant psychosocial risk factors for late life depressive disorders, including life events and ongoing difficulties; death of a spouse or other loved one; medical illness and injuries; disability and functional decline: and lack of social contact. Additional evidence suggests that the impact of these psychosocial risk factors on depression can be enhanced or buffered by personal or environmental factors. Although many of these psychosocial risk factors are more prevalent among older than younger adults, it is not clear that their impact on the risk of depression differs by age. Methodological challenges to advancing research on psychosocial risk factors for late life depression are reviewed, including problems related to study designs, sample selection, and measurement. (C) 2002 Society of Biological Psychiatry.