Guidelines of care for the management of primary cutaneous melanoma
Guidelines of care for the management of primary cutaneous melanoma
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DOI：
10.1016/j.jaad.2011.04.031
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发表时间：
2011-11-01
影响因子：
13.8
通讯作者：
Begolka, Wendy Smith
中科院分区：
文献类型：
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作者：
Bichakjian, Christopher K.;Halpern, Allan C.;Begolka, Wendy Smith
原发性皮肤黑色素瘤的发病率几十年来急剧增加。黑色素瘤占皮肤癌相关死亡的大多数，但治疗几乎总是治愈性的早期发现疾病。在这次更新的护理指南中，我们将讨论原发性皮肤黑色素瘤患者的治疗。我们将讨论临床上怀疑为黑色素瘤的病变的活检技术，并为皮肤黑色素瘤的组织病理学解释提供建议。我们将为新诊断的黑色素瘤患者的初始检查和无症状患者的随访中使用实验室和影像学检查提供建议。关于原发性皮肤黑色素瘤的治疗，我们将提供手术切缘的建议，并简要讨论非手术治疗。最后，我们将讨论前哨淋巴结活检的价值和局限性，并提供其在原发性皮肤黑色素瘤患者中使用的建议。（J Am Acad Dermatol 2011;65：1032-47.）
The incidence of primary cutaneous melanoma has been increasing dramatically for several decades. Melanoma accounts for the majority of skin cancer related deaths, but treatment is nearly always curative with early detection of disease. In this update of the guidelines of care, we will discuss the treatment of patients with primary cutaneous melanoma. We will discuss biopsy techniques of a lesion clinically suspicious for melanoma and offer recommendations for the histopathologic interpretation of cutaneous melanoma. We will offer recommendations for the use of laboratory and imaging tests in the initial workup of patients with newly diagnosed melanoma and for follow-up of asymptomatic patients. With regard to treatment of primary cutaneous melanoma, we will provide recommendations for surgical margins and briefly discuss nonsurgical treatments. Finally, we will discuss the value and limitations of sentinel lymph node biopsy and offer recommendations for its use in patients with primary cutaneous melanoma. (J Am Acad Dermatol 2011;65:1032-47.)