Rectal adenocarcinoma: assessment of tumour involvement of the lateral resection margin by MRI of resected specimen
Rectal adenocarcinoma: assessment of tumour involvement of the lateral resection margin by MRI of resected specimen
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DOI：
10.1259/bjr.72.853.10341684
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发表时间：
1999-01-01
影响因子：
2.6
通讯作者：
Hindmarsh, T
中科院分区：
文献类型：
--
作者：
Blomqvist, L;Rubio, C;Hindmarsh, T
本研究的目的是探讨 MRI 是否可以预测切除的直肠癌标本的侧切缘肿瘤受累情况。使用相控阵表面线圈在临床 1.5 T MR 系统上对全直肠系膜切除后获得的 26 个标本进行矢状面和轴向面检查。测量肿瘤穿透最深点与侧切缘之间的最短距离。该距离称为 LRM。结果与巨大组织病理切片数字图像的测量结果相关。还计算淋巴结和淋巴结转移的总数。八个组织病理学标本中的 LRM 小于或等于 1 毫米（非根治性切除肿瘤考虑的距离）。在切除标本的 MR 图像上。其中 7 个样本的 LRM 小于或等于 1 毫米。 II 标本中 MR 检查中的 LRM 比组织病理学巨型切片中的 LRM 更短。切除标本的MR预测侧切缘肿瘤受累（LRM小于或等于I mm）的敏感性、特异性、阳性和阴性预测值分别为88%、78%、64%和93'%。 MR 无法准确预测淋巴结转移的存在。然而，结论是，当切除的直肠标本超过 1 mm 时，可以通过 MRI 预测无肿瘤侧切除边缘的存在。
The aim of the present study was to investigate whether MRI could predict tumour involvement of the lateral resection margin on resected rectal cancer specimens. 26 specimens obtained after total mesorectal excision were examined in the sagittal and axial plane on a clinical 1.5 T MR system using phased-array surface coils. The shortest distance between the deepest point of tumour penetration and the lateral resection margin was measured. This distance is referred to as LRM. The results were correlated to measurements on digital images of giant histopathological sections. The total number of lymph nodes and lymph node metastases was also counted. LRM was less than or equal to 1 mm (a distance considered for non-radically excised tumours) in eight of the histopathological specimens. On MR images of the resected specimen. LRM was less than or equal to 1 mm in seven of these specimens. LRM was shorter in MR examinations than in histopathological giant sections in Il specimens. The sensitivity, specificity, positive and negative predictive values for prediction of tumour involvement of the lateral resection margin (LRM less than or equal to I mm) by MR of the resected specimen were 88%, 78%, 64% and 93'%,, respectively. Presence of lymph node metastases could not accurately be predicted by MR. However, it is concluded that the presence of a tumour free lateral resection margin can be predicted by MRI of resected rectal specimens when this exceeds 1 mm.