Dietary fat, fiber, vegetable, and micronutrients are associated with overall survival in postmenopausal women diagnosed with breast cancer
Dietary fat, fiber, vegetable, and micronutrients are associated with overall survival in postmenopausal women diagnosed with breast cancer
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DOI：
10.1207/s15327914nc5502_3
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发表时间：
2006-01-01
影响因子：
2.9
通讯作者：
Anton-Culver, Hoda
中科院分区：
文献类型：
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作者：
McEligot, Archana Jaiswal;Largent, Joan;Anton-Culver, Hoda
相对较少的研究评估了饮食摄入量与乳腺癌诊断后生存率之间的关系。我们调查了饮食，包括膳食脂肪（能量百分比），纤维蔬菜和水果摄入量，以及微量营养素（叶酸，类胡萝卜素和维生素C）对乳腺癌患者总生存率的影响。受试者为1994年至1995年间诊断为乳腺癌的绝经后妇女（N = 516），平均生存时间为80个月（SD：18）。受试者在诊断前一年完成了食物频率问卷。考克斯比例风险模型被用来衡量饮食摄入量和乳腺癌诊断后任何原因导致的死亡之间的关系。在多变量分析中，我们发现，与总脂肪、纤维蔬菜和水果的最低三分位数相比，最高三分位数的死亡风险比[HR和95%置信区间（Cl）]为3.12（95%CI = 1.79-5.44）、0.48（95%CI = 0.27-0.86）、0.57（95%CI = 0.35-0.94）和0.63（95%CI = 0.38-1.05）（P
Relatively few studies have assessed the relationship between dietary intakes and survival after breast cancer diagnosis. We investigated the influence of diet, including dietary fat (percentage energy), fiber vegetable, and fruit intakes, and micronutrients (folate, carotenoids, and vitamin C) on overall survival in women diagnosed with breast cancer. Subjects were postmenopausal women diagnosed with breast cancer (N = 516) between 1994 and 1995 with a mean survival time of 80 mo (SD: 18). Subjects completed a food frequency questionnaire for the year prior to diagnosis. Cox proportional hazards models were used to measure the relationship between dietary intakes and death due to any cause after breast cancer diagnosis. In the multivariate analysis, we found that the hazard ratio [HR and 95% confidence interval (Cl)] of dying in the highest tertile compared to the lowest tertile of total fat, fiber vegetable, and fruit was 3.12 (95% CI = 1.79-5.44), 0.48 (95% CI = 0.27-0.86), 0.57 (95% CI = 0.35-0.94), and 0.63 (95% CI = 0.38-1.05), respectively (P