A seasonal variation in the incidence of ruptured abdominal aortic aneurysms
A seasonal variation in the incidence of ruptured abdominal aortic aneurysms
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DOI：
10.1016/s1078-5884(98)80205-0
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发表时间：
1998-05-01
影响因子：
5.7
通讯作者：
Collin, J
中科院分区：
文献类型：
--
作者：
Ballaro, A;Cortina-Borja, M;Collin, J
目的：为了发现腹主动脉瘤破裂的发病率是否存在季节性变化。设计：使用余弦回归模型回顾性分析了每月因腹主动脉瘤破裂而死亡的人数。设置：英格兰和威尔士。受试者：根据死亡证明数据，19599名在1991年1月至1995年12月期间死于腹主动脉瘤破裂的患者。干预措施：None.Results:腹主动脉瘤破裂的发病率存在季节性变化，冬季为高峰（p = 0.003）。男性和女性的腹主动脉瘤破裂的比例从超过12比1下降到低于60岁的年龄低于5比1超过80岁的年龄。结论：有一个季节性变化的发病率记录腹主动脉瘤的死亡在英格兰和威尔士，在寒冷的冬季死亡的高峰。其根本原因尚不清楚，但高血压和吸烟是主动脉瘤破裂的诱发因素。在寒冷的天气里，暴露于烟草烟雾中的程度更大，高血压患者的血压在冬季会达到峰值。
Objective: To discover whether there is a seasonal variation in the incidence of rupture of abdominal aortic aneurysms.Design: Deaths per month due to rupture of abdominal aortic aneurysm were analysed retrospectively using a cosinor regression model.Setting: England and Wales.Subjects: 19599 patients who died from rupture of abdominal aortic aneurysm between January 1991 and December 1995 according to death certification data.Interventions: None.Results: A seasonal variation in the incidence of rupture of abdominal aortic aneurysm occurs, with a peak in winter (p = 0.003). The ratio of rupture of abdominal aortic aneurysm in males and females decreased from more than 12 to 1 below age 60 years to less than 5 to 1 over age 80 years.Conclusions: There is a seasonal variation in the incidence of recorded deaths from abdominal aortic aneurysm in England and Wales, with a peak of deaths in the cold winter months. The underlying cause is unknown, but hypertension and tobacco smoking are predisposing factors to aortic aneurysm rupture. Exposure to tobacco smoke is known to be greater indoors in cold weather and there is a winter peak of blood pressure in hypertensive patients.