Retrieving accurate and distorted memories: Neuroimaging evidence for effects of emotion
Retrieving accurate and distorted memories: Neuroimaging evidence for effects of emotion
复制标题
DOI：
10.1016/j.neuroimage.2005.03.038
复制
发表时间：
2005-08-01
期刊：
影响因子：
5.7
通讯作者：
Schacter, DL
中科院分区：
文献类型：
--
作者：
Kensinger, EA;Schacter, DL
虽然边缘系统的活动与成功的情绪信息编码有关，但它是否与成功的提取有关还不太清楚。本fMRI研究评估的影响，情绪的神经过程中从事检索准确相比，扭曲的记忆。在扫描之前，参与者（16名年轻人）观看了中性的名字（例如，青蛙）和情感（例如，蛇）的对象，并形成了一个命名的对象的心理形象。他们看到了一半物体的照片。在fMRI扫描过程中，参与者看到物体名称，并指出他们是否看到了相应的照片。当参与者错误地指出一张照片是否被研究过时，就会发生记忆扭曲（错误归因）。一些区域的活动（例如，L前海马）与情感和中性项目的准确提取（正确归因>错误归因）有关。然而，在其他区域的活动对应于准确的检索，特别是对情感项目（例如，在R杏仁核/杏仁周围皮质和L眶额皮质中）或对于中性项（例如，外侧下前额叶皮层和右侧后海马）。结果表明，情绪的显着性调制过程中从事准确的检索和边缘区的活动对应于准确的记忆分配的情绪项目。据我们所知，这项研究是第一个证明边缘参与检索和准确的记忆归因之间的联系。(c)2005年爱思唯尔公司All rights reserved.
While limbic activity is known to be associated with successful encoding of emotional information, it is less clear whether it is related to successful retrieval. The present fMRI study assessed the effects of emotion on the neural processes engaged during retrieval of accurate compared to distorted memories. Prior to the scan, participants (16 young adults) viewed names of neutral (e.g., frog) and emotional (e.g., snake) objects and formed a mental image of the object named. They were shown photos of half of the objects. During the fMRI scan, participants saw object names and indicated whether or not they had seen the corresponding photo. Memory distortions (misattributions) occurred when participants incorrectly indicated whether or not a photo had been studied. Activity in some regions (e.g., L anterior hippocampus) was related to accurate retrieval (correct attributions > misattributions) for emotional and neutral items. However, activity in other regions corresponded with accurate retrieval specifically for emotional items (e.g., in R amygdala/periamygdaloid cortex and L orbitofrontal cortex) or for neutral items (e.g., in lateral inferior prefrontal cortex and R posterior hippocampus). Results indicate that emotional salience modulates the processes engaged during accurate retrieval and that activity in limbic regions corresponds with accurate memory assignment for emotional items. To our knowledge, this study is the first to demonstrate a link between limbic engagement at retrieval and accurate memory attribution. (c) 2005 Elsevier Inc. All rights reserved.