NATURAL-HISTORY OF SUDDEN SENSORINEURAL HEARING-LOSS
NATURAL-HISTORY OF SUDDEN SENSORINEURAL HEARING-LOSS
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DOI：
10.1177/000348947708600406
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发表时间：
1977-01-01
影响因子：
1.4
通讯作者：
SIMMONS, FB
中科院分区：
文献类型：
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作者：
MATTOX, DE;SIMMONS, FB
这是一项针对突发性特发性感音神经性耳聋患者的前瞻性深入研究。我们发现，65%的人完全自发地恢复到功能性听力水平，并且不依赖于任何类型的药物治疗。大多数在14天内完成，许多在最初几天内完成。可以根据初始听力图的斜率(低频损失比高频损失更好)、8 kHz的听力、血沉、在某些情况下的空间定向障碍症状和言语辨别分数来预测预后。听力和前庭测试异常之间的相关性很差，除了低活动量热症。与年龄(除高龄外)、既往呼吸道感染无关。高血压、糖尿病或其他慢性病。我们的结论是，耳蜗根尖和耳蜗基底部损失的行为有一个根本的不同，低频率的听力恢复总是比高频好，由于自发性恢复率高，寻求外淋巴瘘的鼓膜切开术应该推迟10天，除非有进行性听力损失，并且目前推荐的治疗方法，特别是组胺，对结果没有任何影响。
This is a prospective in-depth study of patients with sudden idiopathic sensorineural hearing loss. We found that 65% recover completely to functional hearing levels spontaneously and independent of any type of medical treatment. The majority do so within 14 days and many within the first few days. Prognosis can be predicted according to the slope of the initial audiogram (low-frequency losses do better than high-frequency losses), hearing at 8 kHz, erythrocyte sedimentation rates, in some select instances spatial disorientation symptoms, and speech discrimination scores. There was a very poor correlation between hearing and vestibular test abnormalities, except hypoactive calorics. There were no correlations with age (excepting the very elderly), with antecedent respiratory infections. hypertension, diabetes, or other chronic diseases. We conclude that there is a fundamental difference in the behavior of apical and basal cochlea losses, that hearing recovery is always better at low than at high frequencies, that because of the high spontaneous recovery rates, tympanotomies seeking perilymph fistulas should be delayed ten days unless there is a progressive hearing loss, and that none of the current recommended treatments, especially histamine, have any effect on the outcome.