Bioinspired Fiber Networks With Tunable Mechanical Properties by Additive Manufacturing
Bioinspired Fiber Networks With Tunable Mechanical Properties by Additive Manufacturing
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DOI：
10.1115/1.4062451
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发表时间：
2023-08-01
影响因子：
2.6
通讯作者：
Notbohm，Jacob
中科院分区：
文献类型：
--
作者：
Sarkar，Mainak;Notbohm，Jacob
柔性生物纤维网络由于其可调节的力学性能，在生物医学工程和材料设计中具有巨大的潜力。然而，现有的整合仿生网络建模和制造的策略并没有考虑生物聚合物网络固有的微观结构紊乱，这限制了调整其机械性能的能力。为了填补这一空白，我们开发了一种方法来生成模拟I型胶原蛋白的非周期纤维网络的计算机模型，准备提交给增材制造。纤维网络的模型是用脚本语言创建的，其中关键的几何特征，如连通性、纤维长度和纤维截面可以很容易地调整，以实现所需的机械行为，即预紧诱导的剪切增强。首先用有限元软件预测了加劲，然后使用基于软树脂的数字光处理技术的商用3D打印机制作了具有代表性的网络。在一种新型的测试装置上验证了这种网络的加筋响应，该装置能够测试不同水平的单轴预张力下试件的剪切刚度。结果表明，在预制网络中，明显的预张力导致剪切刚度增加，单轴预张力导致小应变剪切刚度增加2.65倍。本文中描述的策略解决了当前生物启发纤维网络建模的挑战，并且可以很容易地与制造技术的进步相结合，以制造真正复制生物聚合物网络机械响应的材料。
Soft bioinspired fiber networks offer great potential in biomedical engineering and material design due to their adjustable mechanical behaviors. However, existing strategies to integrate modeling and manufacturing of bioinspired networks do not consider the intrinsic microstructural disorder of biopolymer networks, which limits the ability to tune their mechanical properties. To fill in this gap, we developed a method to generate computer models of aperiodic fiber networks mimicking type I collagen ready to be submitted for additive manufacturing. The models of fiber networks were created in a scripting language wherein key geometric features like connectivity, fiber length, and fiber cross section could be easily tuned to achieve desired mechanical behavior, namely, pretension-induced shear stiffening. The stiffening was first predicted using finite element software, and then a representative network was fabricated using a commercial 3D printer based on digital light processing technology using a soft resin. The stiffening response of the fabricated network was verified experimentally on a novel test device capable of testing the shear stiffness of the specimen under varying levels of uniaxial pretension. The resulting data demonstrated clear pretension-induced stiffening in shear in the fabricated network, with uniaxial pretension ofresulting in a factor of 2.65 increase in the small strain shear stiffness. The strategy described in this article addresses current challenges in modeling bioinspired fiber networks and can be readily integrated with advances in fabrication technology to fabricate materials truly replicating the mechanical response of biopolymer networks.