Periconceptional Folic Acid Use and Its Effects on Neural Tube Defects - Five Counties, Shanxi Province, China, 2010-2016.
Periconceptional Folic Acid Use and Its Effects on Neural Tube Defects - Five Counties, Shanxi Province, China, 2010-2016.
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DOI：
10.46234/ccdcw2023.154
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发表时间：
2023-09-08
期刊：
影响因子：
4.7
通讯作者：
Li Z
中科院分区：
文献类型：
--
作者：
Zhang Y;Liu J;Zhang L;Jin L;Li Z
强有力的证据表明，补充叶酸围怀孕期可能会降低胎儿神经管缺陷（NTDs）的风险。在NTD病例组和对照组中，超过一半的母亲在围受孕期使用叶酸补充剂，两组之间没有显着差异。然而，与对照母亲相比，患有NTD病例的母亲在服用叶酸方面依从性较差的比例显着更高。在面临意外怀孕的妇女和教育水平较低的妇女中观察到叶酸摄入量的依从性显着降低。应加强对育龄妇女叶酸作用的普及教育，以提高围产期补充叶酸的依从性，进一步降低NTD的患病率。
Robust evidence indicates that supplementing with folic acid periconceptionally may decrease the risk of neural tube defects (NTDs) in fetuses. Over half of the mothers in both the NTD case group and the control group utilized folic acid supplements during the periconceptional period, showing no notable variations between the two groups. However, there was a significantly higher percentage of mothers with NTD cases who exhibited poor compliance in folic acid use compared to control mothers. A significantly lowered compliance with folic acid intake was observed among women facing unintended pregnancies and those with lower education levels. Universal education regarding folic acid action for women of childbearing age should be strengthened to improve compliance with folic acid supplementation in the periconceptional period and further reduce the prevalence of NTDs.
影响因子：
4.7
作者：
Song Q;Wei J;Wang J;Zhang L;Liu X;Zhang Y;Li N;Li Z
通讯作者：
Li Z