Poder preditivo do MoCa na avaliação neuropsicológica de pacientes com diagnóstico de demência
Poder preditivo do MoCa na avaliação neuropsicológica de pacientes com diagnóstico de demência
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预防痴呆症诊断的神经心理学患者
DOI：
10.1590/1809-9823.2014.13123
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发表时间：
2014
影响因子：
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通讯作者：
José Eduardo Martinelli
中科院分区：
文献类型：
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作者：
J. Cecato;José Maria Montiel;D. Bartholomeu;José Eduardo Martinelli
本研究旨在将受过 4 年以上教育的老年人的神经测量测试关联起来，并评估 MoCA 在诊断阿尔茨海默病和轻度认知障碍 (MCI) 方面的准确性。它评估了2010年4月至2012年12月在老年病学和老年学研究所接受治疗的136名老年患者。使用的仪器包括简易精神状态检查（MMSE）、剑桥认知考试（CAMCOG）、时钟绘图测试（CDT）、言语流畅性测试、老年抑郁量表、普费弗功能活动问卷（PFAQ）和蒙特利尔认知评估（MoCA）。 ROC 曲线分析用于建立截断值和 Pearson 相关系数，以将 MoCA 与其他测试进行比较。结果表明，MoCA 是区分阿尔茨海默病和 MCI 的最佳测试。敏感性和特异性分别为 82.2% 和 92.3%。相关性测试分析表明，MoCA 与巴西已经验证并广泛应用的其他测试具有很强的相关性。 MoCA 测试显示出区分 AD 和 MCI 的最大预测价值，也区分 MCI 和正常对照。此外，MoCA 与年龄变量以及 MMSE、CAMCOG、CDT、言语流利度和 PFAQ 测试显着相关，这些工具已在巴西得到验证并广泛使用。
This study aimed to correlate neuropsicometric tests in elderly over 4 years of schooling and assess MoCA accuracy in diagnosing Alzheimer's disease and mild cognitive impairment (MCI). It evaluated 136 elderly patients treated at the Institute of Geriatrics and Gerontology, from April 2010 to December 2012. The instruments used were the Mini-Mental State Examination (MMSE), Cambridge Cognitive Examination (CAMCOG), Clock Drawing Test (CDT), Verbal Fluency test, Geriatric Depression Scale, Pfeffer Functional Activities Questionnaire (PFAQ), and Montreal Cognitive Assessement (MoCA). ROC curve analysis was used to establish cutoffs and the Pearson correlation coefficient to compare the MoCA with the other tests. The results showed that the MoCA was the best test to differentiate Alzheimer's disease from MCI. The sensitivity and specificity found were 82.2% and 92.3%, respectively. The analysis of the correlation test showed that MoCA is strongly correlated with other tests already validated and wide applied in Brazil. The MoCA test showed the greatest predictive value to differentiate AD from MCI and also differ MCI from normal controls. Furthermore, MoCA was significantly correlated with the age variable and MMSE, CAMCOG, CDT, Verbal Fluency and PFAQ tests, instruments that are already validated and widely used in Brazil.