Hydrothermal Conversion of One-Photon-Fluorescent Poly(4-vinylpyridine) into Two-Photon-Fluorescent Carbon Nanodots
Hydrothermal Conversion of One-Photon-Fluorescent Poly(4-vinylpyridine) into Two-Photon-Fluorescent Carbon Nanodots
复制标题
单光子荧光聚（4-乙烯基吡啶）水热转化为双光子荧光碳纳米点
作者：
Lawrence K
合成并表征了一种新型的具有双光子荧光的富N，O杂原子碳纳米材料。这种新型碳纳米颗粒是由单光子荧光聚（4-乙烯基吡啶）前体（P4 VP）通过水热转化制备的。具有不均匀粒径（范围从亚6至20 nm，一些聚集体高达200 nm）的纳米颗粒（cP 4VP点）在不同溶剂中表现出强荧光性质，并且还研究了其在细胞培养基中的应用。cP 4VP点在细胞环境中保留其固有荧光，并在细胞中表现出2.0 ± 0.9 ns的平均激发态寿命。cP 4VP点进入HeLa细胞，不会对细胞外膜造成显著损伤。它们为成像应用和/或药物递送提供单光子或双光子荧光合成支架。
A novel two-photon-fluorescent N,O-heteroatom-rich carbon nanomaterial has been synthesized and characterized. The new carbon nanoparticles were produced by hydrothermal conversion from a one-photon-fluorescent poly(4-vinylpyridine) precursor (P4VP). The carbonized particles (cP4VP dots) with nonuniform particle diameter (ranging from sub-6 to 20 nm with some aggregates up to 200 nm) exhibit strong fluorescence properties in different solvents and have also been investigated for applications in cell culture media. The cP4VP dots retain their intrinsic fluorescence in a cellular environment and exhibit an average excited-state lifetime of 2.0 ± 0.9 ns in the cell. The cP4VP dots enter HeLa cells and do not cause significant damage to outer cell membranes. They provide one-photon or two-photon fluorescent synthetic scaffolds for imaging applications and/or drug delivery.