Paraneoplastic necrotizing myelopathy in a patient with advanced esophageal cancer: An autopsied case report
Paraneoplastic necrotizing myelopathy in a patient with advanced esophageal cancer: An autopsied case report
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DOI：
10.1016/j.jns.2009.02.324
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发表时间：
2009-05-15
影响因子：
4.4
通讯作者：
Masaki, Tsutomu
中科院分区：
文献类型：
--
作者：
Urai, Yoshiteru;Matsumoto, Kouichi;Masaki, Tsutomu
我们报告了文献中第一例与食管癌相关的副肿瘤性坏死性脊髓病尸检病例。患者患有急性弛缓性截瘫和尿潴留，在皮质类固醇的作用下双腿力量恢复良好。 MRI 显示起病时颈部至中胸段脊髓钆后增强的特征性病变，但从未有过报道。综上所述，这些结果表明副肿瘤性坏死性脊髓病存在潜在的自身免疫机制。 (C) 2009 Elsevier B.V. 保留所有权利。
We report the first autopsied case of paraneoplastic necrotizing myelopathy associated with esophageal cancer in the literature. The patient had acute flaccid paraplegia and urinary retention, and had a good recovery of strength of both legs in response to corticosteroids. MRI showed a characteristic lesion with post-gadolinium enhancement of the cervical to mid-thoracic spinal cord at the onset, which has never been reported. Taken together, these results suggest that there is an underlying autoimmune mechanism in paraneoplastic necrotizing myelopathy. (C) 2009 Elsevier B.V. All rights reserved.