Arsenic-related hepatic angiosarcoma.
Arsenic-related hepatic angiosarcoma.
复制标题
DOI：
10.1002/ajim.4700020108
复制
发表时间：
1981-01-01
影响因子：
3.5
通讯作者：
Popper, H
中科院分区：
文献类型：
--
作者：
Falk, H;Caldwell, G G;Popper, H
20世纪40年代和50年代德国葡萄酒商的几个小型尸检系列的数据和一些病例报告先前表明砷是肝血管肉瘤（HAS）的原因。在美国对HAS死亡的全国性回顾中，我们发现了7例长期使用福勒氏溶液（无机亚砷酸钾）的病例，这为砷暴露与HAS的关联提供了进一步的支持。一项对长期接受福勒氏液治疗的人群进行的流行病学研究可能证实了这种关联。
Data from several small autopsy series in German vintners in the 1940s and 1950s and a number of case reports have previously suggested that arsenic is a cause of hepatic angiosarcoma (HAS). In a nationwide review of deaths from HAS in the United States, we identified seven cases with a history of prolonged use of Fowler's solution (inorganic potassium arsenite), which provide further support for the association of arsenic exposure and HAS. An epidemiologic study of a cohort of individuals treated long-term with Fowler's solution might confirm this association.