BONELIKE HYDROXYAPATITE INDUCTION BY A GEL-DERIVED TITANIA ON A TITANIUM SUBSTRATE
BONELIKE HYDROXYAPATITE INDUCTION BY A GEL-DERIVED TITANIA ON A TITANIUM SUBSTRATE
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DOI：
10.1111/j.1151-2916.1994.tb05407.x
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发表时间：
1994-05-01
影响因子：
3.9
通讯作者：
KOKUBO, T
中科院分区：
文献类型：
--
作者：
LI, PJ;KANGASNIEMI, I;KOKUBO, T
在商业纯（c. p.）钛诱导羟基磷灰石从模拟体液（SBF，亚稳磷酸钙溶液）形成到其表面上。诱导的磷灰石类似于骨磷灰石，因为它结晶不良，缺钙，含碳酸盐。此外，碳酸根（CO 32-）基团进入磷灰石晶格并位于PO 43-和OH-的位置以取代这些离子基团，类似于骨磷灰石的（CO 32-）基团。因此，由凝胶衍生的二氧化钛诱导的磷灰石被认为是骨样的。化学刺激，源于丰富的羟基基团和负电荷的二氧化钛凝胶的表面，被认为是负责骨磷灰石诱导。凝胶二氧化钛是模拟体液中类骨磷灰石的有效诱导剂，具有骨结合的潜力。
Gel-derived titania coating on commercial pure (c.p.) titanium induces hydroxyapatite formation onto its surface from a simulated body fluid (SBF, a metastable calcium phosphate solution). The induced apatite is similar to bone apatite in that it is poorly crystallized, calcium-deficient, and carbonate-containing. Furthermore, the carbonate (CO32-) groups go into the apatite lattice and lie at the positions of PO43- and OH- to replace these ionic groups, resembling the (CO32-) groups of bone apatite. Therefore, the apatite induced by the gel-derived titania is said to be bone-like. A chemical stimulation, stemming from abundant hydroxyl groups and negative charges at the surface of the titania gel, is believed to be responsible for the bonelike apatite induction. The potential of bone-bonding is predicted for the gel-derived titania, for it is an efficient bone-like apatite inducer in the SBF.