ENDOCRINE ABNORMALITIES IN THALASSEMIA MAJOR
ENDOCRINE ABNORMALITIES IN THALASSEMIA MAJOR
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DOI：
10.1001/archpedi.1979.02130050041009
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发表时间：
1979-01-01
影响因子：
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通讯作者：
ORTEGA, JA
中科院分区：
文献类型：
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作者：
COSTIN, G;KOGUT, MD;ORTEGA, JA
对16例β-地中海贫血患者的内分泌功能评估表明，低促性腺激素减退、甲状旁腺功能减退和ACTH储备减少是常见的表现，而生长激素和甲状腺储备减少则较少见。含铁血黄素沉着症引起的内分泌腺损伤似乎是研究患者内分泌功能障碍的主要原因。
Endocrine function evaluations in 16 patients with .beta.-thalassemia indicate that hypogonadotropic hypogonadism, hypoparathyroidism and reduced ACTH reserve occur frequently, whereas reduced growth hormone and thyroid reserve are less common manifestations. Hemosiderosis-induced damage of the endocrine glands seems to be the main cause for endocrine dysfunction in the patients studied.