Role of Porphyromonas Gingivalis in Periodontal Disease
Role of Porphyromonas Gingivalis in Periodontal Disease
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DOI：
10.1016/s1646-2890(07)70136-x
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发表时间：
2007-07-01
影响因子：
0.3
通讯作者：
Cabral, Cristina Trigo
中科院分区：
文献类型：
--
作者：
Carvalho, Carlos;Cabral, Cristina Trigo
牙龈卟啉单胞菌是一种厌氧菌，存在于多种牙周病中。其致病性依赖于毒力因子，如菌毛、多糖、毒素产生等，这些毒力因子在龈下生物膜上定植，导致组织入侵和破坏。在过去的十年中，许多研究都在评估这种微生物在牙周病中的重要性，以及微生物学诊断在牙周病鉴定中的作用。本文就该细菌的致病性、感染机制、传播途径和微生物学诊断等方面作一综述。
Porphyromonas gingivalis is an anaerobic strict bacteria present in diverse forms of periodontal disease. Its pathogenicity is dependent on virulence factors such as fimbriae, lypopolysaccharide, toxin production among others, that take to the colonization of the subgingival biofilm, with consequent tissue invasion and destruction. In the last decade, many have been the works developed in a way to evaluate the importance of this micro organism in periodontal disease, as well as the interest of the microbiological diagnosis in its identification. This paper has the aim to make a revision of the characteristics of this bacteria that make her as a potential periodontal pathogenic, focusing on its etiopathogenicity, mechanisms of infection, ways of transmission and microbiological diagnosis.