Sample sizes for estimation in clinical research
Sample sizes for estimation in clinical research
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DOI：
10.1002/pst.125
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发表时间：
2004-07-01
影响因子：
1.5
通讯作者：
Patterson, SD
中科院分区：
文献类型：
--
作者：
Julious, SA;Patterson, SD
所有临床调查都应给出样本量的理由。然而，有时试验的目的是为了估计效果，以便计划以后的确定研究。本文描述了设计研究的计算，其中人们希望通过使用总体响应周围的置信区间来采用估计方法。对预计采用标准形式的数据进行了计算。版权所有2004 John Wiley Sons Ltd
A sample size justification should be given for all clinical investigations. However, sometimes the objective of a trial is to estimate an effect with a view to planning a later definitive study. This paper describes the calculations for designing studies where one wishes to adopt an estimation approach through using confidence intervals around the overall response. Calculations are given for data anticipated to take a Normal form. Copyright (C) 2004 John Wiley Sons Ltd.