Viral aetiology and epidemiology of acute respiratory infections in hospitalized Saudi children

Viral aetiology and epidemiology of acute respiratory infections in hospitalized Saudi children
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DOI:
10.1093/tropej/44.2.100
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发表时间:
1998-04-01
影响因子:
2
通讯作者:
Ramia, S
Ramia, S
中科院分区:
医学4区
文献类型:
--
作者:
Bakir, TMF;Halawani, M;Ramia, S

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在三年期间(1993年4月至1996年3月),共有1429名5岁以下的沙特儿童因急性呼吸道感染(阿尔蒂)而被收住利雅得哈立德国王大学医院。在522例(37%)病例中可以检测到病毒,其中呼吸道合胞病毒(RSV)最常见(79%),其次是3型副流感病毒(8%)。甲型流感、II型流感和腺病毒的检测分别占6%、3%和2%。除3型副流感病毒外,呼吸道病毒的活动高峰在冬季(10月至2月),3型副流感病毒全年均可检测到,但流行病可在一年中最热的月份(6月至8月)发生,此时温度可超过40摄氏度。在研究的第一年,对137名沙特儿童的临床表现、病原体类型和年龄之间的关系进行了评估1993年4月至1994年3月,我们的大多数病例表现为毛细支气管炎(58%),而只有26%的人患有支气管肺炎,(0-6个月),呼吸道合胞病毒是毛细支气管炎病例的主要病原体(88%)。
A total of 1429 Saudi children of either sex and under 5 years of age who were admitted to King Khalid University Hospital, Riyadh during a three year period (April 1993-March 1996) with complaints suggestive of acute respiratory tract infections (ARTI) were investigated for viral aetiology of the infection. Viruses could be detected in 522 (37 per cent) cases with respiratory syncytial virus (RSV) the most commonly detected (79 per cent) followed by parainfluenza type 3 (8 per cent). Detection of influenza A, Il and adenoviruses accounted for 6 per cent, 3 per cent and 2 per cent respectively. Except for parainfluenza virus type 3 the peak of activity of the respiratory viruses was during the winter months (October-February), Parainfluenza virus type 3 could be detected all year round but epidemics can occur in the hottest months of the year (June-August) when the temperature can exceed 40 degrees C. Association between clinical manifestation, type of causative agent, and age was evaluated in 137 infected Saudi children in the first year of the study (April 1993-March 1994), The majority of our cases presented with bronchiolitis (58 per cent) while only 26 per cent had bronchopneumonia, There was a significant association between bronchiolitis and lower age groups (0-6 months), with RSV as the major causative agent of bronchiolitis cases (88 per cent).