Jasmonate response decay and defense metabolite accumulation contributes to age-regulated dynamics of plant insect resistance.
Jasmonate response decay and defense metabolite accumulation contributes to age-regulated dynamics of plant insect resistance.
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DOI：
10.1038/ncomms13925
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发表时间：
2017-01-09
影响因子：
16.6
通讯作者：
Chen XY
中科院分区：
文献类型：
--
作者：
Mao YB;Liu YQ;Chen DY;Chen FY;Fang X;Hong GJ;Wang LJ;Wang JW;Chen XY
动物的免疫力随着年龄的增长而下降，但对植物对食草动物的抗性的时间调节知之甚少。植物激素茉莉酸(JA)是植物抗虫性的关键调节因子。在这里，我们表明JA响应在拟南芥中逐渐衰退。我们发现这种衰退受miR156靶向的Squamosa启动子结合蛋白-LIKE9(SPL9)组蛋白的调节，SPL9组蛋白可以与JA ZIM结构域(JAZ)蛋白相互作用，包括JAZ3。随着SPL9水平的逐渐增加，JAZ3积累，JA反应减弱。我们提供的证据表明，这一途径有助于幼树的抗虫性。然而，有趣的是，尽管JA反应衰退，但随着硫代葡萄糖苷积累的增加，较老的植物仍然对鳞翅目的多面手棉铃虫和专门的小菜蛾具有相对更强的抗性。我们提出了一个模型，在这个模型中，防御化合物的结构性积累在补偿植物成熟过程中与年龄相关的JA反应衰减方面发挥了作用。动物的免疫力随着年龄的增长而下降，但人们对衰老如何影响植物的免疫力知之甚少。在这里，毛等人。研究表明，随着植物年龄的增长，对主要的昆虫防御激素JA的反应性会下降，但随着植物积累硫代葡萄糖苷等次生代谢物，昆虫的抗药性仍然会增加。
Immunity deteriorates with age in animals but comparatively little is known about the temporal regulation of plant resistance to herbivores. The phytohormone jasmonate (JA) is a key regulator of plant insect defense. Here, we show that the JA response decays progressively in Arabidopsis. We show that this decay is regulated by the miR156-targeted SQUAMOSA PROMOTER BINDING PROTEIN-LIKE9 (SPL9) group of proteins, which can interact with JA ZIM-domain (JAZ) proteins, including JAZ3. As SPL9 levels gradually increase, JAZ3 accumulates and the JA response is attenuated. We provide evidence that this pathway contributes to insect resistance in young plants. Interestingly however, despite the decay in JA response, older plants are still comparatively more resistant to both the lepidopteran generalist Helicoverpa armigera and the specialist Plutella xylostella, along with increased accumulation of glucosinolates. We propose a model whereby constitutive accumulation of defense compounds plays a role in compensating for age-related JA-response attenuation during plant maturation. Immunity deteriorates with age in animals but less is known about how aging affects immunity in plants. Here, Mao et al. show that responsiveness to the major insect defense hormone JA declines as plants age, but insect resistance still increases as plants accumulate secondary metabolites such as glucosinolates.