Spontaneous baroreflex sensitivity in young and older people during voluntary and electrically evoked isometric exercise
Spontaneous baroreflex sensitivity in young and older people during voluntary and electrically evoked isometric exercise
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DOI：
10.1093/ageing/31.5.359
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发表时间：
2002-09-01
期刊：
影响因子：
6.7
通讯作者：
White, MJ
中科院分区：
文献类型：
--
作者：
Carrington, CA;White, MJ
背景：在年轻人中，心脏迷走神经压力反射敏感性在等长运动中改变。我们研究了随着年龄的增长而降低的静息压力反射敏感性是否在运动过程中也发生了类似的改变。对8例青年人进行了心迷走神经压力感受性反射敏感性测定（年龄+/-SEM，25+/-1.7岁）和9岁以上（61 ± 3.0岁）受试者，在随意和电诱发等长运动期间使用序列分析结果：在这两种情况下的所有阶段，压力反射敏感性显着降低，在老年组与年轻组相比。（中位数（四分位距），自愿7.0（4.4）vs 3.6（3.8）ms.mmHg（-1），运动后循环闭塞9.0（8.2）vs 4.6（4.0）ms.mmHg（-1）;电诱发6.6（10.6）vs 3.2（3.6）ms·mmHg（-1），运动后循环闭塞8.3（7.7）vs 2.9（2.2）ms·mmHg（-1），青年vs老年; P
Background: in young people, cardiovagal baroreflex sensitivity alters during isometric exercise. We investigated whether the reduced resting baroreflex sensitivity seen with increasing age is similarly altered during exercise.Methods: cardiovagal baroreflex sensitivity was examined in 8 young (age+/-SEM, 25+/-1.7 years) and 9 older (61+/-3.0 years) subjects, using sequence analysis during voluntary and electrically evoked isometric exercise (at 30% maximum voluntary strength) and during subsequent post-exercise circulatory occlusion.Results: in all phases of both conditions, baroreflex sensitivity was significantly reduced in the older group compared with the young group. (Median (interquartile range), voluntary 7.0 (4.4) vs 3.6 (3.8) ms.mmHg(-1), post-exercise circulatory occlusion 9.0 (8.2) vs 4.6 (4.0) ms.mmHg(-1); electrically evoked 6.6 (10.6) vs 3.2 (3.6) ms.mmHg(-1), post-exercise circulatory occlusion 8.3 (7.7) vs 2.9 (2.2) ms.mmHg(-1), young vs older respectively; P