The Influence of Psychiatric Comorbidity on Perioperative Outcomes Following Primary Total Hip and Knee Arthroplasty; A 17-year Analysis of the National Hospital Discharge Survey Database
The Influence of Psychiatric Comorbidity on Perioperative Outcomes Following Primary Total Hip and Knee Arthroplasty; A 17-year Analysis of the National Hospital Discharge Survey Database
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DOI：
10.1016/j.arth.2014.08.034
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发表时间：
2015-02-01
影响因子：
3.5
通讯作者：
Barsoum, Wael K.
中科院分区：
文献类型：
--
作者：
Buller, Leonard T.;Best, Matthew J.;Barsoum, Wael K.
关于精神疾病（包括抑郁、焦虑、痴呆和精神分裂症）对全髋关节置换术（THA）和膝关节置换术（TKA）围手术期结局的影响，研究存在冲突。使用美国国家医院出院调查评估了1990年至2007年期间THA或TKA患者的精神并发症发生率、院内不良事件、出院处置和死亡率。确定了一个代表8，379，490例患者的队列，并使用多变量回归分析进行了分析。抑郁症、痴呆和精神分裂症的诊断与不良事件的几率增加相关（P < 0.001）。精神分裂症和抑郁症与围手术期输血的几率较高相关（P < 0.001）。所有精神科合并症均与非常规出院几率较高相关（P < 0.001）。痴呆的诊断与较高的住院死亡率相关（P < 0.001）。(C)2014爱思唯尔公司All rights reserved.
Studies conflict regarding the impact of psychiatric illnesses including depression, anxiety, dementia and schizophrenia on perioperative outcomes following total hip (THA) and knee arthroplasty (TKA). Psychiatric comorbidity incidence, in-hospital adverse events, discharge disposition, and mortality were assessed for THA or TKA patients between 1990 and 2007 using the US National Hospital Discharge Survey. A cohort representative of 8,379,490 patients was identified and analyzed using multivariable regression analysis. Diagnoses of depression, dementia and schizophrenia were associated with increased odds of adverse events (P < 0.001). Schizophrenia and depression were associated with higher odds of perioperative blood transfusion (P < 0.001). All psychiatric comorbidities were associated with higher odds of non-routine discharge (P < 0.001). Diagnosis of dementia was associated with higher in-hospital mortality (P < 0.001). (C) 2014 Elsevier Inc. All rights reserved.