Varroa destructor is an effective vector of Israeli acute paralysis virus in the honeybee, Apis mellifera
Varroa destructor is an effective vector of Israeli acute paralysis virus in the honeybee, Apis mellifera
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DOI：
10.1099/vir.0.023853-0
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发表时间：
2011-01-01
影响因子：
3.8
通讯作者：
Chen, Yanping
中科院分区：
文献类型：
--
作者：
Di Prisco, Gennaro;Pennacchio, Francesco;Chen, Yanping
以色列急性麻痹病毒（IAPV）是蜂群衰竭失调（CCD）的重要标志。在目前的工作中，我们提供了第一个证据，表明瓦螨破坏者具有IAPV的复制能力，并能够在蜜蜂中传播IAPV。蜜蜂在接触携带病毒的瓦螨后感染了IAPV。蜜蜂体内IAPV拷贝数与蜂螨密度和蜂螨暴露时间呈正相关。此外，我们发现螨病毒关联可能会降低宿主免疫力，从而促进病毒复制水平的升高。本研究明确了蜂螨在IAPV传播中的积极作用，为蜜蜂感染IAPV的流行病学研究提供了新的思路。
The Israeli acute paralysis virus (IAPV) is a significant marker of honeybee colony collapse disorder (CCD). In the present work, we provide the first evidence that Varroa destructor is IAPV replication-competent and capable of vectoring IAPV in honeybees. The honeybees became infected with IAPV after exposure to Varroa mites that carried the virus. The copy number of IAPV in bees was positively correlated with the density of Varroa mites and time period of exposure to Varroa mites. Further, we showed that the mite virus association could possibly reduce host immunity and therefore promote elevated levels of virus replication. This study defines an active role of Varroa mites in IAPV transmission and sheds light on the epidemiology of IAPV infection in honeybees.