A CAROTANE SESQUITERPENE AS A POTENT MODULATOR OF THE MAXI-K CHANNEL FROM ARTHRINIUM-PHAESOSPERMUM
A CAROTANE SESQUITERPENE AS A POTENT MODULATOR OF THE MAXI-K CHANNEL FROM ARTHRINIUM-PHAESOSPERMUM
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DOI：
10.1016/0960-894x(95)00104-2
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发表时间：
1995-04-06
影响因子：
2.7
通讯作者：
SINGH, SB
中科院分区：
文献类型：
--
作者：
ONDEYKA, JG;BALL, RG;SINGH, SB
从Arthrinium phaeospermum中分离出的Maxi-K通道的有效调节剂已通过光谱方法确定为胡萝卜素类倍半萜。X射线晶体学研究表明，该化合物与先前发现的抗真菌剂CAF-603相同。
A potent modulator of the Maxi-K channel, isolated from Arthrinium phaeospermum, has been determined to be a carotane sesquiterpene by spectroscopic means. X-ray crystallographic studies demonstrated this compound as being identical to CAF-603, previously discovered as an antifungal agent.