Effect of supplemental vitamin E on the peripheral blood leukocyte population in Japanese Black calves.
Effect of supplemental vitamin E on the peripheral blood leukocyte population in Japanese Black calves.
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DOI：
10.1292/jvms.15-0060
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发表时间：
2015-08
期刊：
影响因子：
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通讯作者：
Ohtsuka H
中科院分区：
文献类型：
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作者：
Otomaru K;Saito S;Endo K;Kohiruimaki M;Ohtsuka H
我们研究了补充维生素E对日本黑犊牛外周血白细胞群的影响。对同一农场饲养的26头小牛进行了研究。他们被分为两组; 13头小牛接受300 IU/天口服维生素E从1至3个月大（VE组），和其他13头小牛没有接受维生素E补充剂（对照组）。VE组2月龄和3月龄血清维生素E浓度均显著高于对照组（P <0.01）。维生素E组CD3+、CD4+细胞数高于对照组，3月龄时差异有统计学意义（P <0.05）。VE组CD21+细胞数高于对照组，2月龄时差异有统计学意义（P <0.05）。VE组CD335+细胞数有高于对照组的趋势。3月龄和4月龄时，VE组的CD 8+细胞和CD 14+细胞数量有高于对照组的趋势。本研究表明，补充维生素E的哺乳日本黑牛可能会影响外周血中某些免疫细胞类型的数量。
We investigated the effect of supplemental vitamin E on the peripheral blood leukocyte population in Japanese Black calves. Twenty-six calves kept at the same farm were studied. They were divided into two groups; thirteen calves received 300 IU/day of vitamin E orally from 1 to 3 months of age (VE group), and the other thirteen calves did not receive the vitamin E supplement (control group). The VE group showed a higher serum vitamin E concentration at 2 and 3 months of age compared with the control group (P<0.01). The numbers of CD3+ cells and CD4+ cells were higher in the VE group than in the control group, and the difference was statistically significant at 3 months of age (P<0.05). The numbers of CD21+ cells were higher in the VE group than in the control group, and the difference was statistically significant at 2 months of age (P<0.05). The numbers of CD335+ cells tended to be higher in the VE group than in the control group. The numbers of CD8+ cells and CD14+ cells tended to be higher in the VE group than in the control group at 3 and 4 months of age. This study demonstrated that the supplementation of suckling Japanese Black calves with vitamin E might affect the numbers of some immune cell types in the peripheral blood.