Design of a Resonant Radiofrequency Driver for Ion Transmission in a Desktop Mass Spectrometer and Its Application in Volatile Organic Compound Determination
Design of a Resonant Radiofrequency Driver for Ion Transmission in a Desktop Mass Spectrometer and Its Application in Volatile Organic Compound Determination
复制标题
台式质谱仪中离子传输谐振射频驱动器的设计及其在挥发性有机物测定中的应用
DOI：
10.1080/00032719.2019.1711385
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发表时间：
2020-01
影响因子：
2
通讯作者：
Tian Di
中科院分区：
文献类型：
--
作者：
Qi Guochen;Li Qingyun;Liu Guangda;Qiu Chunling;Long Tao;Tian Di
摘要从高压离子源区到低压质谱区的离子转换效率是质谱仪性能的重要指标之一。为了降低离子损耗和提高离子灵敏度，在国产飞行时间质谱仪(TOF-MS)中设计了一种射频驱动器，该驱动器采用电阻-电感-电容(RLC)谐振放大模式来驱动射频四极杆(RFQ)。射频驱动器的峰间电压Vp在50~1000 V范围内连续调节，相对标准偏差为2.5‰。通过对苯、甲苯和对二甲苯混合物的表征，对质谱仪中射频四极杆的性能进行了评估。苯、甲苯和对二甲苯的检出限分别为0.07、0.05和0.04 ppbv。此外，通过对新装修房间和呼气中挥发性有机物(VOCs)的测定，对射频四极杆的性能和稳定性进行了评估。结果表明，研制的射频驱动器具有在质谱仪中应用的潜力。
Abstract The ion transformation efficiency from a high-pressure ion source region to a low-pressure mass analysis region is one of the important indices for the mass spectrometer performance. To decrease the ion loss and improve the sensitivity of ions, a radiofrequency driver was designed in a home-made time-of-flight mass spectrometer (TOF-MS), which adopted a resistance-inductance-capacitance (RLC) resonant amplification pattern to drive the radiofrequency quadrupole (RFQ). The peak-to-peak voltage Vp-p of the radiofrequency driver was continuously adjusted from 50 to 1000 V with a relative standard deviation of 2.5‰. The performance of the radiofrequency quadrupole in the mass spectrometer was assessed by the characterization of a mixture of benzene, toluene, and p-xylene. The limits of detection for benzene, toluene, and p-xylene were 0.07, 0.05, and 0.04 ppbv, respectively. Moreover, the performance and stability of radiofrequency quadrupole were assessed by the determination of volatile organic compounds (VOCs) in newly decorated rooms and exhaled breath. The results indicated that the developed radiofrequency driver has potential for use in mass spectrometers.
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影响因子：
1.8
作者：
P. Franceschi;L. Penasa;D. Ascenzi;D. Bassi;M. Scotoni;P. Tosi
通讯作者：
P. Franceschi;L. Penasa;D. Ascenzi;D. Bassi;M. Scotoni;P. Tosi
DOI：
10.1515/zna-1953-0710
发表时间：
1953-07
期刊：
Zeitschrift für Naturforschung A
影响因子：
--
作者：
W. Paul;H. Steinwedel
通讯作者：
W. Paul;H. Steinwedel
影响因子：
7.4
作者：
Wang Yan;Hua Lei;Li Qingyun;Jiang Jichun;Hou Keyong;Wu Chenxin;Li Haiyang
通讯作者：
Li Haiyang
DOI：
10.1016/1044-0305(92)87067-9
发表时间：
1992-05-01
影响因子：
3.2
作者：
DOUGLAS, DJ;FRENCH, JB
通讯作者：
FRENCH, JB
影响因子：
2
作者：
K. Chandra;P. S. Ramanjaneyulu;C. Yadav;A. S. Kulkarni;Y. S. Sayi;K. L. Ramakumar
通讯作者：
K. Chandra;P. S. Ramanjaneyulu;C. Yadav;A. S. Kulkarni;Y. S. Sayi;K. L. Ramakumar