Chronic intraaneurysmal pressure measurement: an experimental method for evaluating the effectiveness of endovascular aortic aneurysm exclusion.

Chronic intraaneurysmal pressure measurement: an experimental method for evaluating the effectiveness of endovascular aortic aneurysm exclusion.
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慢性动脉瘤内压力测量:评估血管内主动脉瘤排除有效性的实验方法。

DOI:
10.1016/s0741-5214(97)70182-4
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发表时间:
1997
影响因子:
4.3
通讯作者:
Veith,FJ
Veith,FJ
中科院分区:
医学2区
文献类型:
--
作者:
Sanchez,LA;Faries,PL;Marin,ML;Ohki,T;Parsons,RE;Marty,B;Soeiro,D;Olivieri,S;Veith,FJ

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目的评价和比较两种不同的血管内支架隔绝术后动脉瘤内压(IAP)的变化。方法8只杂种犬,将一个3 × 3cm的聚四氟乙烯(PTFE)动脉瘤作为肾下主动脉的间置支架缝合。植入动脉瘤壁的压力传感器允许连续电子IAP监测。4个动脉瘤用由PTFE移植物和2个Palmaz支架(PTFE-EG)制成的经腔放置的血管内移植物排除,3个用钽-涤纶血管内移植物(TD-EG)排除,1个用标准PTFE移植物(PTFE-Surg)手术治疗。狗观察了18至50天(平均37.5天),并进行了评估后,手术与双工和螺旋CT scanns.ResultsAll移植成功排除动脉瘤没有移植物周围的渠道或泄漏记录的动脉造影和双工和计算机断层扫描。所有PTFE-EG修复后的平均IAP均显著低于(p < 0.001)平均体循环压力。此外,平均IAP减少是显着更大(p < 0.005)在PTFE-EG组比在TD-EG group.ConclusionsAneurysm排除与PTFE-EG显着降低IAP,这样做显着优于TD-EG,并接近IAP减少标准修复获得。这种压力降低对于有效防止动脉瘤破裂是必要的。(J Vasc Surg 1997 26:222-30.)
PurposeTo evaluate and compare the intraaneurysmal pressure (IAP) after exclusion using two different endovascular grafts.MethodsEight mongrel dogs had a 3 × 3 cm polytetrafluoroethylene (PTFE) aneurysm sewn as an interposition graft of the infrarenal aorta. A pressure transducer implanted into the aneurysm wall permitted continuous electronic IAP monitoring. Four aneurysms were excluded with a transluminally placed endovascular graft made of a PTFE graft and two Palmaz stents (PTFE-EG), three were excluded with a tantalum-Dacron endovascular graft (TD-EG), and one was surgically treated with a standard PTFE graft (PTFE-Surg). The dogs were observed for 18 to 50 days (mean, 37.5 days) and were evaluated after surgery with duplex and spiral computed tomographic scans.ResultsAll grafts successfully excluded the aneurysms without perigraft channels or leaks as documented by arteriogram and duplex and computed tomographic scans. The mean IAPs after repair with all PTFE-EGs were significantly lower (p < 0.001) than the mean systemic pressures. In addition, the mean IAP reduction was significantly greater (p < 0.005) in the PTFE-EG group than in the TD-EG group.ConclusionsAneurysm exclusion with PTFE-EG significantly lowered IAP, did so significantly better than the TD-EG, and approached the IAP reduction obtained by standard repair. Such pressure reduction is necessary for effective protection against aneurysm rupture. (J Vasc Surg 1997 26:222-30.)