RATS (RATTUS-NORVEGICUS) SELECTIVELY BRED TO DIFFER IN AVOIDANCE-BEHAVIOR ALSO DIFFER IN RESPONSE TO NOVELTY STRESS, IN GLYCEMIC CONDITIONING, AND IN REWARD CONTRAST
RATS (RATTUS-NORVEGICUS) SELECTIVELY BRED TO DIFFER IN AVOIDANCE-BEHAVIOR ALSO DIFFER IN RESPONSE TO NOVELTY STRESS, IN GLYCEMIC CONDITIONING, AND IN REWARD CONTRAST
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DOI：
10.1016/s0163-1047(89)90782-6
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发表时间：
1989-03-01
期刊：
影响因子：
--
通讯作者：
ROWAN, GA
中科院分区：
文献类型：
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作者：
FLAHERTY, CF;ROWAN, GA
采用Brush（F.）选择性饲养的锡拉丘兹高回避（SHA）和锡拉丘兹低回避（SLA）大鼠的行为。R.布拉什，J.C. Froehlich和P. Sakellaris，1979，Behavior Genetics，9，309-316）来区分回避行为。当暴露于新环境时，SLA大鼠显示出更大的血糖升高;暴露于该环境7天后，SHA大鼠中有适应性的证据，但SLA大鼠中没有; SHA大鼠在血糖调节过程中显示出高血糖条件反应，SLA大鼠没有显示出调节的证据，但具有更高的总体血糖水平;当从32%到4%的蔗糖时，两种品系的大鼠在完成行为中均显示出可靠的连续负对比效应，但SLA大鼠的对比度更大;利氮卓的给药消除了SLA大鼠的负对比度，但对SHA大鼠的对比度没有影响; SLA大鼠可靠地比SHA大鼠重。行为差异被认为是在两个菌株之间的情绪反应差异的背景下。
The behavior of the Syracuse high avoidance (SHA) and Syracuse low avoidance (SLA) rats, selectively bred by Brush (F. R. Brush, J. C. Froehlich, and P. Sakellaris, 1979, Behavior Genetics, 9, 309-316) to differ in avoidance behavior, was examined in several different tasks. The SLA rats showed a greater elevation in plasma glucose when exposed to a novel environment; after 7 days of exposure to this environment there was evidence of habituation in the SHA rats but not in the SLA rats; the SHA rats showed a hyperglycemic conditioned response in a glycemic conditioning procedure, the SLA rats showed no evidence of conditioning but had higher overall levels of plasma glucose; both strains showed reliable successive negative contrast effects in consummatory behavior when shifted from 32 to 4% sucrose, but the contrast was larger in the SLA rats; the administration of chlordiazepoxide eliminated negative contrast in the SLA rats but had no effect on contrast in the SHA rats; and the SLA rats were reliably heavier than the SHA rats. The behavioral differences were considered in the context of difference in emotional reactivity between the two strains.