Hollow permeable polysiloxane capsules: a novel approach for fabrication, guest encapsulation and morphology studies
Hollow permeable polysiloxane capsules: a novel approach for fabrication, guest encapsulation and morphology studies
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DOI：
10.1039/b315999j
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发表时间：
2004-05
影响因子：
--
通讯作者：
Huigang Wang;Pin Chen;Xiao-ming Zheng
中科院分区：
文献类型：
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作者：
Huigang Wang;Pin Chen;Xiao-ming Zheng
首先通过将甲基三甲氧基硅烷和二甲基二甲氧基硅烷单体连续共缩合到聚二甲基硅氧烷上，然后通过暴露于溶剂除去模板化的聚二甲基硅氧烷，制备了直径在180至210 nm之间的中空可渗透聚硅氧烷胶囊。通过透射电子显微镜（TEM）和原子力显微镜（AFM）证实了聚合物颗粒的形态。首先提出了一种可能的模型，以获得最佳的说明胶囊。消炎痛最初是使用溶解共扩散方法封装到胶囊中的。
Hollow permeable polysiloxane capsules with diameters between 180 and 210 nm were firstly fabricated by consecutively cocondensed methyltrimethoxysilane and dimethyldimethoxysilane monomers onto polydimethylsiloxane and subsequently removing the templated polydimethylsiloxane by exposure to solvents. The morphology of the polymer particles was demonstrated by transmission electron micrographs (TEM) and atomic force microscopy (AFM). One possible model was firstly proposed to gain the best illustration of the capsules. Indomethacin was originally encapsulated into the capsules using a solute-co-diffusion method.