Comparison of commercial isotonic fluids intravenously administered to rehydrate fasted bullocks
Comparison of commercial isotonic fluids intravenously administered to rehydrate fasted bullocks
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DOI：
10.1292/jvms.59.689
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发表时间：
1997-08-01
影响因子：
1.2
通讯作者：
Iwabuchi, S
中科院分区：
文献类型：
--
作者：
Suzuki, K;Ajito, T;Iwabuchi, S
在这项研究中使用荷斯坦公牛来比较五种市售胃肠外液体的有效性（盐水IS，Hartmann’s IH，5%-葡萄糖5G，Ringers IR，和1/2林格氏和2.5%葡萄糖组合溶液RG）在纠正与禁食48小时引起的脱水相关的紊乱中的作用。用30 ml/kg的复方甘草酸苷（30 ml/kg）对禁食48 h引起的公牛脱水，分别于禁食前、0、15、30、45、60、90、120、240、360 min、和开始液体给药后24小时。禁食48小时导致体重和相对血浆容量（rPV）显著降低，分别约为7.72%和21.93%。给药期间，rPV从空腹后约88.1%逐渐增加至113.0%，组间无显著差异。在5G和RG组中观察到液体给药结束后rPV迅速下降。液体给药试验结果表明，1/2林格氏液和2.5%葡萄糖混合液抑制血液酸化，不改变血清电解质平衡，并诱导肾脏对葡萄糖的适当重吸收率，因此被认为是对2天以上无食欲的成年牛进行补液的最佳选择。
Holstein bullocks were used in this study to compare the effectiveness of five commercial parenteral fluids (saline IS, Hartmann's IH, 5%-glucose 5G, Ringers IR, and 1/2 Ringer's and 2.5% glucose combination solutions RG) in correcting the disturbances associated with dehydration induced by fasting for 48 hr. These five commercial fluids (30 ml/kg) were given to bullocks with dehydration induced by fasting for 48 hr. Arterial and venous blood samples were taken before fasting, and at 0, 15, 30, 45, 60, 90, 120, 240, 360 min, and 24 hr after initiation of fluid administration. Fasting for 48 hr induced significant reductions in body weight and relative plasma volume (rPV), of approximately 7.72 and 21.93%, respectively. During the administration period, rPV showed a progressive increase from approximately 88.1% after fasting to 113.0% with no significantly differences between groups. A rapid decrease of rPV when fluid administration has been finished was observed in the 5G and RG groups. The results of the fluid administration trial showed that the 1/2 Ringer's and 2.5% glucose combination solution inhibited the acidification of the blood, produced no change in the electrolyte balance of serum, and induced a proper reabsorption rate of glucose in the renals, and was therefore considered the best choice for the rehydration of adult cattle which have had no appetite for over 2 days.