Norms for Change in Episodic Memory as a Prerequisite for the Diagnosis of Mild Cognitive Impairment (MCI)
Norms for Change in Episodic Memory as a Prerequisite for the Diagnosis of Mild Cognitive Impairment (MCI)
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DOI：
10.1037/a0014079
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发表时间：
2009-03-01
期刊：
影响因子：
2.4
通讯作者：
Monsch, Andreas U.
中科院分区：
文献类型：
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作者：
Blaesi, Stefan;Zehnder, Antoinette E.;Monsch, Andreas U.
国际轻度认知障碍工作组（Winblad 等人，2004 年，第 243 页）提出的轻度认知障碍 (MCI) 新诊断标准将“客观认知任务随时间下降的证据”列为诊断标志之一，这意味着需要重复的神经心理学测试。本研究旨在比较不同的纵向变化评估方法，该方法基于 366 名认知健康参与者（237 名男性，129 名女性）在基线和 2 年后使用德国版本的加州语言学习测试（Delis、Kramer、Kaplan 和 Ober，1987 年）的表现进行检查。年龄、教育程度、性别和基线表现都被考虑在内。两年后实践效果显着。事实证明，控制实践效果和均值回归的变化的正常范围优于其他可靠的变化指标。这种新方法可以更有效地解释神经心理功能的变化，从而诊断 MCI。
The new diagnostic criteria for mild cognitive impairment (MCI) from the International Working Group on Mild Cognitive Impairment (Winblad et al., 2004, p. 243) list "evidence of decline over time in objective cognitive tasks" as one diagnostic sign, implying the repeated neuropsychological testing. This study aimed to compare different assessment methods of longitudinal change based on the performances of 366 cognitively healthy participants (237 men, 129 women) examined with a German version of the California Verbal Learning Test (Delis, Kramer, Kaplan, & Ober, 1987) at baseline and 2 years later. Age, education, gender, and baseline performance were taken into account. Results revealed marked practice effects after 2 years. Normal ranges for change that controls for practice effects and regression to the mean proved to be superior to other reliable change indexes. This new method allows for more valid interpretation of change in neuropsychological functioning and thus diagnosis of MCI.