Allergic sensitization during early life: Concordance between ImmunoCAP and ISAC results.
Allergic sensitization during early life: Concordance between ImmunoCAP and ISAC results.
复制标题
DOI：
10.1016/j.jaip.2020.12.028
复制
发表时间：
2021-05
期刊：
影响因子：
--
通讯作者：
Camargo CA Jr
中科院分区：
文献类型：
--
作者：
Arroyo AC;Robinson LB;Geller RJ;Rudders SA;Sullivan AF;Hasegawa K;Camargo CA Jr
生命早期的过敏性敏化可以预测过敏性疾病的发展。1过敏原致敏的检测方法有多种，包括皮肤点刺试验和血清特异性ige （sIgE）测定。目前，商业上可用的sIgE测量方法包括：1)将sIgE量化到附着在固相测定法上的单个过敏原或成分（例如，ImmunoCAP）； 2)在微阵列中同时将sIgE量化到多个过敏原成分（例如，immunosolid -phase allergen Chip [ISAC]）。虽然ImmunoCAP已在临床和研究环境中使用多年，但ISAC已越来越多地用于儿科队列，因为使用较少的血液检测sIgE，以广泛的过敏原。然而，尚不清楚免疫cap和ISAC是否在生命早期，特别是婴儿期产生一致的结果。
Early life allergic sensitization may predict development of allergic disease. 1 Various testing methods are used to detect allergen sensitization, including skin prick testing and the measurement of serum specific-IgE (sIgE). Currently, commercially-available methods to measure sIgE include: 1) quantifying sIgE to a single allergen or component attached to a solid phase assay (eg, ImmunoCAP) and 2) quantifying sIgE to multiple allergen components simultaneously in a microarray (eg, Immuno Solid-phase Allergen Chip [ISAC]). 2 While ImmunoCAP has been used for many years in clinical and research settings, ISAC has increasingly been utilized in pediatric cohorts due to the detection of sIgE to a wide array of allergens using a smaller amount of blood. 1 However, it is not known whether ImmunoCAP and ISAC yield concordant results during early life, especially during infancy.
登录
查看更多内容
DOI：
10.1183/13993003.00152-2016
发表时间：
2016-11
期刊：
The European respiratory journal
影响因子：
--
作者：
Hasegawa K;Mansbach JM;Ajami NJ;Espinola JA;Henke DM;Petrosino JF;Piedra PA;Shaw CA;Sullivan AF;Camargo CA Jr;the MARC-35 Investigators
通讯作者：
the MARC-35 Investigators
DOI：
10.1348/000711006x126600
发表时间：
2008-05-01
影响因子：
2.6
作者：
Gwet, Kilem Li
通讯作者：
Gwet, Kilem Li
影响因子：
12.4
作者：
Jeong, KY;Lee, J;Yong, TS
通讯作者：
Yong, TS
影响因子：
14.2
作者：
Wilson, Jeffrey M.;Workman, Lisa;Platts-Mills, Thomas A. E.
通讯作者：
Platts-Mills, Thomas A. E.
影响因子：
14.2
作者：
Kelly, Suzanne M.;Karsh, Jacob;Yang, William H.
通讯作者：
Yang, William H.