Five-year blood pressure trajectories of survivors of the tsunami following the Great East Japan Earthquake in Iwate
Five-year blood pressure trajectories of survivors of the tsunami following the Great East Japan Earthquake in Iwate
复制标题
岩手县东日本大地震后海啸幸存者的五年血压轨迹
DOI：
10.1038/s41440-020-00607-9
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发表时间：
2021
影响因子：
5.4
通讯作者：
Motoyuki Nakamura
中科院分区：
文献类型：
--
作者：
Tomohiro Takahashi;F. Tanaka;H. Shimoda;K. Tanno;K. Sakata;Shuko Takahashi;Y. Yonekura;A. Ogawa;S. Kobayashi;Osamu Shimooki;Motoyuki Nakamura
遭受重大损害的海啸幸存者是否在灾难发生后立即和中长期内血压(BP)上升尚不清楚。我们将海啸幸存者分成两组，一组重新安置(严重损害)，另一组没有重新安置(损害很小)，并比较了灾难发生后头5年两组之间的BP轨迹。在42831名居民中，3914人接受了2010至2015年的评估。亚组分析是在2010-2015年间没有降压药物信息的2037名受试者中进行的(没有降压药物组)。用线性混合模型比较有无再移位组的BP轨迹。所有受试者的多变量调整后的平均收缩压在灾后显著降低，无论是搬迁组(2010年：130.6 毫米汞柱，2015年：124.8 毫米汞柱)和未搬迁组(2010年：130.7 毫米汞柱，2015年：126.7 毫米汞柱)。移位与SBP时间点的交互作用显著(P= 0.017)。在非降压药物组中，灾后第2、3、5年搬迁亚组的SBP值显著低于未搬迁亚组。结果表明，日本东部大地震海啸幸存者的SBP值在灾后中长期呈下降趋势，搬迁组SBP下降幅度大于未搬迁组。
Whether tsunami survivors who suffered substantial damage experienced increases in blood pressure (BP) immediately after the disaster and in the medium to long term is unclear. We divided tsunami survivors into groups, those who relocated (substantial damage) and those who did not (little damage) and compared the BP trajectories between the groups over the first 5 years after the disaster. Of the 42,831 residents, 3914 were assessed from 2010 to 2015. Subgroup analysis was performed among the 2037 subjects with no information on antihypertensive medications between 2010 and 2015 (no antihypertensive medication group). The BP trajectories in the relocation and no relocation groups were compared using linear mixed models. The multivariate-adjusted mean systolic BP (SBP) values for all subjects significantly decreased after the disaster in both the group who relocated (2010: 130.6 mmHg, 2015: 124.8 mmHg) and the group who did not relocate (2010: 130.7 mmHg, 2015: 126.7 mmHg). The interaction between relocation and time points on SBP was significant (P= 0.017). In the no antihypertensive medication group, the SBP values in the subgroup who relocated were significantly lower in the second, third, and fifth years after the disaster than those in the subgroup who did not relocate. It was concluded that the SBP values of survivors of the tsunami caused by Great East Japan Earthquake decreased in the medium to long term after the disaster, and the group who relocated had a larger decrease in SBP than the group who did not relocate.