Recent Advances in Radical Carbonylation
Recent Advances in Radical Carbonylation
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DOI：
10.1002/9783527831883.ch12
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发表时间：
2022-01
期刊：
影响因子：
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通讯作者：
S. Sumino;T. Fukuyama;I. Ryu
中科院分区：
文献类型：
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作者：
S. Sumino;T. Fukuyama;I. Ryu
无论起始自由基是烷基自由基、烯基自由基还是芳基自由基，自由基羰基化都产生酰基自由基作为第一中间体，通过羰基化转化为各种羰基化合物，如醛、酮、酯、酰胺和其他一些化合物。本章概述了自由基羰基化的最新进展以及对以往成就的快速概述。原子转移羰基化（ATC）不需要自由基介质，现在已经刺激了许多有用的过渡金属/自由基杂化体系的发展，其中关键的羰基化步骤是自由基羰基化，而不是迁移CO插入到金属-烷基键上。本章还讨论了基于单电子转移体系的自由基羰基化的新趋势，即电子转移羰基化（ETC）。
The radical carbonylation, irrespective of whether the starting radicals being the alkyl, alkenyl, or aryl radicals, produces acyl radicals as the first intermediates, which are transformed to a variety of carbonyl compounds, such as aldehydes, ketones, esters, amides, and some other compounds via carbonylation. This chapter overviews the recent advances in radical carbonylation together with quick overview of previous achievements. The atom‐transfer carbonylation (ATC), which does not require radical mediators, has now stimulated the developments of many useful transition‐metal/radical hybrid systems, in which the key carbonylation step is radical carbonylation rather than migratory CO insertion to metal–alkyl bonds. New trends of radical carbonylation based on one‐electron transfer system is also discussed in this chapter, which is well featured as electron transfer carbonylation (ETC).