ENDOSCOPIC SUBMUCOSAL DISSECTION FOR THE RELIABLE EN BLOC RESECTION OF COLORECTAL MUCOSAL TUMORS

ENDOSCOPIC SUBMUCOSAL DISSECTION FOR THE RELIABLE EN BLOC RESECTION OF COLORECTAL MUCOSAL TUMORS
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内镜粘膜下剥离术可靠地整块切除结直肠粘膜肿瘤

DOI:
10.1111/j.1443-1661.2004.00396.x
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发表时间:
2004
影响因子:
5.3
通讯作者:
M. Omata
M. Omata
中科院分区:
医学2区
文献类型:
--
作者:
N. Yahagi;M. Fujishiro;A. Imagawa;N. Kakushima;M. Iguchi;M. Omata

文献摘要

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在日本,只要术前明确诊断,颗粒型横向扩散肿瘤(LST - G)已积极进行有计划的分段切除。然而,对于凹陷性病变(如IIc病变)和非颗粒型横向扩散肿瘤(LST - NG),整体切除是可取的,因为它们具有相当高的粘膜下浸润风险,需要精确的组织病理学评估。内镜下粘膜剥离术(ESD)已发展成为胃肠道粘膜肿瘤的整体切除方法,尤其在胃病变中得到广泛应用。虽然大肠在结构和技术上存在困难,但我们在进行准备工作的同时进行了ESD整体切除;内窥镜,器械,局部注射等等。ESD是一种可靠的技术,可以对胃肠道粘膜病变进行整体切除,甚至对早期结直肠癌的治疗也有很大的可能性。
Scheduled piecemeal resection has been actively conducted for granular type laterally spreading tumor (LST‐G) in Japan, as long as a definite preoperative diagnosis is made. However, en bloc resection is desirable for depressed lesions (e.g. IIc lesion) as well as non‐granular type laterally spreading tumor (LST‐NG) since they have considerable high risk for submucoasl invasion and require precise histopathological evaluation. Endoscopic submucosal dissection (ESD) has been developed for the en bloc resection of mucosal tumors of gastrointestinal tract and widely applied especially in gastric lesions. Although the large intestine involves structural and technical difficulties, we conducted en bloc resection by ESD while exercising sorts of ingenuity for preparation; endoscopes, instruments, local injections, and others. ESD is a reliable technique that allows en bloc resection of gastrointestinal mucosal lesions, and even has a splendid possibility for the treatment of early stage colorectal cancer.