EFFECTS OF GAMMA-IRRADIATION ON THE INITIAL MECHANICAL AND MATERIAL PROPERTIES OF GOAT BONE-PATELLAR TENDON-BONE ALLOGRAFTS
EFFECTS OF GAMMA-IRRADIATION ON THE INITIAL MECHANICAL AND MATERIAL PROPERTIES OF GOAT BONE-PATELLAR TENDON-BONE ALLOGRAFTS
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DOI：
10.1002/jor.1100090209
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发表时间：
1991-03-01
影响因子：
2.8
通讯作者：
NOYES, FR
中科院分区：
文献类型：
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作者：
GIBBONS, MJ;BUTLER, DL;NOYES, FR
研究了Co-60 γ射线辐照对骨-髌腱-骨复合体（CU）和髌腱中间体（TM）初始力学性能的影响。 将冷冻标本暴露于2或3 Mrad的伽马辐照。 配对冷冻标本作为动物内对照。 使用四个力学参数评估对CU的治疗效果。 对TM的影响进行了评估，使用光学表面应变分析系统测量的四个材料参数。 在3 Mrad辐照后，复合材料单元的最大力和最大力的应变能分别显著降低27%和40%（p <0.05）。 CU的机械性能没有显着改变，但是，以下2 Mrad的照射。 基于治疗组和对照组之间的个体配对对比，还发现肌腱中间物质的材料特性存在显著差异。 最大应力，最大应变，应变能密度最大应力显着降低后3 Mrad，但不是2 Mrad，照射。 结果提供了重要的“零时间”材料性能数据，这将是有用的，为以后的前交叉韧带重建研究，使用辐照同种异体髌腱在山羊模型和其他动物模型，以及。
The effects of Co-60 gamma irradiation on the initial mechanical properties of the composite bone-patellar tendon-bone unit (CU) and the tendon midsubstance (TM) were studied. Frozen specimens were exposed to either 2 or 3 Mrad of gamma irradiation. Paired frozen specimens served as intraanimal controls. Treatment effects on the CU were assessed using four mechanical parameters. Effects on the TM were assessed using four material parameters measured using an optical surface-strain analysis system. The maximum force and strain energy to maximum force of the composite unit were significantly reduced 27% and 40%, respectively, after 3 Mrad of irradiation (p < .05). Mechanical properties of the CU were not significantly altered, however, following 2 Mrad of irradiation. Based on individual paired contrasts between treatment and control, significant differences were also found in the material properties of the tendon midsubstance. The maximum stress, maximum strain, and strain energy density to maximum stress were significantly reduced following 3 Mrad, but not 2 Mrad, of irradiation. The results provide important "time zero" material property data, which will be useful for later anterior cruciate ligament reconstruction studies using irradiated allograft patellar tendons in the goat model and other animal models as well.