Incarceration and Cancer-Related Outcomes (ICRO) study protocol: using a mixed-methods approach to investigate the role of incarceration on cancer incidence, mortality and quality of care.
Incarceration and Cancer-Related Outcomes (ICRO) study protocol: using a mixed-methods approach to investigate the role of incarceration on cancer incidence, mortality and quality of care.
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DOI：
10.1136/bmjopen-2021-048863
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发表时间：
2021-05-25
期刊：
影响因子：
2.9
通讯作者：
Wang EA
中科院分区：
文献类型：
--
作者：
Puglisi L;Halberstam AA;Aminawung J;Gallagher C;Gonsalves L;Schulman-Green D;Lin HJ;Metha R;Mun S;Oladeru OT;Gross C;Wang EA
监禁与癌症筛查率下降以及出狱后因癌症住院和死亡的风险较高有关。然而，关于监禁与癌症预后和护理质量之间关系的数据缺乏。在监禁和癌症相关结果研究中，我们的目标是对监禁如何影响癌症发病率、死亡率和治疗，以及调节社会经济地位、结构性种族主义和癌症差异之间的关系进行细致入微的理解。我们将采用顺序解释性混合方法研究设计。我们将创建第一个综合链接数据从康涅狄格矫正部门和全州康涅狄格肿瘤登记处。使用关联数据集，我们将检查2005年至2016年康涅狄格州目前被监禁、以前被监禁和从未被监禁的个体之间癌症发病率和诊断阶段的差异。在患有侵袭性癌症的个体中，我们将评估监禁、癌症护理质量和死亡率之间的关系，并将评估监禁状况在多大程度上调节种族、社会经济地位、癌症护理质量和癌症死亡率之间的关系。我们将使用多变量逻辑回归和Cox生存模型，并酌情使用相互作用项。这些结果将为我们对在监禁期间或监禁后不久被诊断为癌症的个人进行深入访谈提供信息，了解他们在惩教系统中接受癌症治疗的经历以及释放后的直接经历。这项定性工作的结果将有助于将数据链接的结果置于背景中。耶鲁大学机构审查委员会（#2000022899）和康涅狄格公共卫生部人类调查委员会批准了这项研究。我们将通过同行评审的出版物以及学术和社区报告来传播研究结果。在审查请求后，将提供对未确定的定量和定性数据集的访问。
Incarceration is associated with decreased cancer screening rates and a higher risk for hospitalisation and death from cancer after release from prison. However, there is a paucity of data on the relationship between incarceration and cancer outcomes and quality of care. In the Incarceration and Cancer-Related Outcomes Study, we aim to develop a nuanced understanding of how incarceration affects cancer incidence, mortality and treatment, and moderates the relationship between socioeconomic status, structural racism and cancer disparities. We will use a sequential explanatory mixed-methods study design. We will create the first comprehensive linkage of data from the Connecticut Department of Correction and the statewide Connecticut Tumour Registry. Using the linked dataset, we will examine differences in cancer incidence and stage at diagnosis between individuals currently incarcerated, formerly incarcerated and never incarcerated in Connecticut from 2005 to 2016. Among individuals with invasive cancer, we will assess relationships among incarceration, quality of cancer care and mortality, and will assess the degree to which incarceration status moderates relationships among race, socioeconomic status, quality of cancer care and cancer mortality. We will use multivariable logistic regression and Cox survival models with interaction terms as appropriate. These results will inform our conduct of in-depth interviews with individuals diagnosed with cancer during or shortly after incarceration regarding their experiences with cancer care in the correctional system and the immediate postrelease period. The results of this qualitative work will help contextualise the results of the data linkage. The Yale University Institutional Review Board (#2000022899) and the Connecticut Department of Public Health Human Investigations Committee approved this study. We will disseminate study findings through peer-reviewed publications and academic and community presentations. Access to the deidentified quantitative and qualitative datasets will be made available on review of the request.
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影响因子：
4.4
作者：
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通讯作者：
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