Temporal trends in ischemic heart disease mortality in 21 world regions, 1980 to 2010: the Global Burden of Disease 2010 study.
Temporal trends in ischemic heart disease mortality in 21 world regions, 1980 to 2010: the Global Burden of Disease 2010 study.
复制标题
DOI：
10.1161/circulationaha.113.004042
复制
发表时间：
2014-04-08
期刊：
影响因子：
37.8
通讯作者：
Naghavi M
中科院分区：
文献类型：
--
作者：
Moran AE;Forouzanfar MH;Roth GA;Mensah GA;Ezzati M;Murray CJ;Naghavi M
缺血性心脏病（IHD）是全球范围内的主要死亡原因。2010年全球疾病负担、风险因素和伤害研究估计了1980年至2010年全球和区域IHD死亡率。IHD死亡率估计的来源是国家级监测、死因推断和生命登记数据。区域收入、代谢和营养风险因素以及其他协变量通过调查和系统评价进行估计。一个估计和验证过程导致了21个世界地区的IHD死亡率的集合模型。在全球范围内，年龄标准化IHD死亡率自20世纪80年代以来一直在下降，高收入地区（特别是澳大拉西亚，西欧和北美）经历了最显着的下降。20世纪90年代，前苏联国家和南亚的标准化IHD死亡率增加，2000年后减少。2010年，东欧和中亚的年龄标准化IHD死亡率最高。2010年，南亚的IHD死亡人数超过任何其他地区。平均而言，与大多数其他地区相比，南亚、北非和中东以及撒哈拉以南非洲的IHD死亡发生在较年轻的年龄。在世界大多数地区，特别是高收入地区，年龄标准化IHD死亡率自1980年以来已显著下降。东欧、中亚和南亚的高年龄标准化IHD死亡率表明，有必要预防和控制这些地区的既定危险因素，并研究IHD死亡率较高的独特行为和环境决定因素。
Ischemic heart disease (IHD) is the leading cause of death worldwide. The Global Burden of Diseases, Risk Factors and Injuries 2010 Study estimated global and regional IHD mortality from 1980 to 2010. Sources for IHD mortality estimates were country-level surveillance, verbal autopsy, and vital registration data. Regional income, metabolic and nutritional risk factors, and other covariates were estimated from surveys and a systematic review. An estimation and validation process led to an ensemble model of IHD mortality for 21 world regions. Globally, age-standardized IHD mortality has declined since the 1980s, and high-income regions (especially Australasia, Western Europe, and North America) experienced the most remarkable declines. Age-standardized IHD mortality increased in former Soviet Union countries and South Asia in the 1990s and attenuated after 2000. In 2010, Eastern Europe and Central Asia had the highest age-standardized IHD mortality rates. More IHD deaths occurred in South Asia in 2010 than in any other region. On average, IHD deaths in South Asia, North Africa and the Middle East, and sub-Saharan Africa occurred at younger ages in comparison with most other regions. In most world regions, particularly in high-income regions, age-standardized IHD mortality rates have declined significantly since 1980. High age-standardized IHD mortality in Eastern Europe, Central Asia, and South Asia point to the need to prevent and control established risk factors in those regions and to research the unique behavioral and environmental determinants of higher IHD mortality.