Prolonged mechanical ventilation after left ventricular assist device implantation: risk factors and clinical implications
Prolonged mechanical ventilation after left ventricular assist device implantation: risk factors and clinical implications
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DOI：
10.1002/ehf2.12428
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发表时间：
2019-06-01
影响因子：
3.8
通讯作者：
Luedike, Peter
中科院分区：
文献类型：
--
作者：
Papathanasiou, Maria;Mincu, Raluca-Ileana;Luedike, Peter
主要心血管手术后未成功撤机与术后发病率和死亡率增加相关。我们的研究旨在确定左心室辅助装置（LVAD）植入后长时间机械通气（PMV）的预测因素和临床意义。方法和结果我们分析了2010年12月至2017年9月在我们中心接受连续流LVAD的患者的数据。PMV定义为LVAD植入后>7天的有创通气持续时间。对PMV的预测因素进行多因素Logistic回归分析。通过Kaplan-Meier方法估计存活率。在研究期间，156例患者在我们中心接受了连续流LVAD。17例患者因早期死亡而被排除（
Aims Unsuccessful weaning from ventilator after major cardiovascular procedures has been shown to be associated with increased post-operative morbidity and mortality. Our study aimed to identify predictors and clinical implications of prolonged mechanical ventilation (PMV) after left ventricular assist device (LVAD) implantation. Methods and results We analysed the data of patients receiving a continuous-flow LVAD in our centre from December 2010 to September 2017. PMV was defined by a duration of invasive ventilation of >7 days after LVAD implantation. Multivariable logistic regression analysis was performed for predictors of PMV. Survival was estimated by the Kaplan-Meier method. During the study period, 156 patients received a continuous-flow LVAD in our centre. Seventeen patients were excluded due to early death (