The building of molecularly imprinted single hole hollow particles: A miniemulsion polymerization approach
The building of molecularly imprinted single hole hollow particles: A miniemulsion polymerization approach
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DOI：
10.1016/j.cej.2018.09.128
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发表时间：
2019-02
影响因子：
15.1
通讯作者：
Zehu Wang;T. Qiu;Longhai Guo;Jun Ye;Lifang He;Xiaoyu Li
中科院分区：
文献类型：
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作者：
Zehu Wang;T. Qiu;Longhai Guo;Jun Ye;Lifang He;Xiaoyu Li
分子印迹聚合物（MIP）由于具有较高的识别效率，其结构设计日益受到人们的关注。我们在这里展示了一个简单的细乳液为基础的聚合，合成单孔中空MIP粒子识别双酚A（BPA）。通过在水性分散体中的一步聚合可以获得均匀的亚微米产物，其中聚合物种子已经在交联剂和功能单体与BPA的模板分子一起的细乳液中溶胀。在通过萃取去除种子和模板分子后，电子显微镜表征显示在凹表面上具有单个孔的碗状颗粒。独特的单孔中空结构是由细乳液液滴中聚合诱导的相分离决定的，并且可以通过单体组分来改变。分子印迹聚合物的特性通过在再结合试验中的分子识别来说明，其中在最佳配方下制备的颗粒在甲醇和水（20：80，v/v）的混合溶液中表现出显著的动力学和对BPA的理想选择性。具有单孔中空结构的MIP微粒在环境和分析领域对BPA的净化具有重要的应用前景。
The structural design on the molecularly imprinted polymers (MIP) has been increasingly concerned because of advanced recognition efficiency. We here demonstrate a facile miniemulsion based polymerization to synthesize single hole hollow MIP particles for the recognition of bisphenol A (BPA). Uniform submicron products can be achieved through one-step polymerization in the aqueous dispersion, where the polymer seed has been swelled in the miniemulsion of the cross-linker and functional monomers together with the template molecules of BPA. After the removal of the seed and the template molecules by extraction, the electron microscopy characterization reveals bowl-like particles with a single hole on the concave surface. The unique single hole hollow structure is determined by the polymerization induced phase separation in the miniemulsion droplets and can be altered by monomer components. The characteristic of MIP is illustrated by the molecular recognition in the rebinding tests, where the particles prepared under the optimal formulation exhibit remarkable kinetics and desirable selectivity towards BPA in the mixed solution of methanol and water (20:80, v/v). The MIP particles with single hole hollow structure would be attractive in environmental and analytic fields for BPA decontamination.