Power Doppler assessment of vascular changes during fracture treatment with low-intensity ultrasound
Power Doppler assessment of vascular changes during fracture treatment with low-intensity ultrasound
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DOI：
10.7863/jum.2003.22.2.145
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发表时间：
2003-02-01
影响因子：
2.3
通讯作者：
Hume, E
中科院分区：
文献类型：
--
作者：
Rawool, NM;Goldberg, BB;Hume, E
Objective.研究能量多普勒超声在低强度超声治疗骨折部位过程中评估血管变化的应用。方法.在6只犬（3对）中，尺骨中段的皮下解剖允许使用往复锯进行对称截骨。3只犬接受治疗，3只用作对照。骨折部位接受1.5 MHz低强度超声（30 mW/cm（2）），每天20分钟，来自治疗超声装置。用灰阶超声评价骨折部位。能量多普勒超声用于评估骨折部位和周围软组织的血流模式。静脉注射超声造影剂。剂量为0.2 mL/kg。结果能量多普勒超声显示，与对照犬相比，治疗犬骨折部位周围血流增加。第7天，处理腿的颜色像素值比对照腿高3倍，第11天，处理腿比对照腿高33%。造影剂给药后的增强在治疗腿中始终高于对照腿。结论.能量多普勒超声显示，在使用和不使用造影剂的情况下，治疗犬骨折部位周围的血管分布增加。
Objective. To study the use of power Doppler sonography for assessing changes in vascularity during treatment of fracture sites with low-intensity ultrasound. Methods. In 6 dogs (3 pairs), subcutaneous dissection of the midshaft of the ulna allowed symmetrical osteotomies to be made with a reciprocation saw. Three dogs were treated and 3 were used as controls. The fracture site was subjected to 1.5-MHz low-intensity ultrasound (30 mW/cm(2)) for 20 minutes daily from a therapeutic ultrasonic device. Gray scale sonography was performed to evaluate the fracture site. Power Doppler sonography was used to assess flow patterns at the fracture site and surrounding soft tissue. A sonographic contrast agent was administered intravenously. The dose was 0.2 mL/kg. Results. Power Doppler sonography showed an increase in flow around the fracture site in the treated dogs compared with that in control dogs. Color pixel values on day 7 were 3-fold higher in treated legs than control legs and on day 11 were 33% higher in treated legs than control legs. Enhancement after contrast agent administration was consistently higher in treated legs than control legs. Conclusions. Power Doppler sonography showed increased vascularity around the fracture sites in treated dogs with and without contrast agent administration.