Relationship between intra-uterine bacterial contamination, endotoxin levels and the development of endometritis in postpartum cows with dystocia or retained placenta
Relationship between intra-uterine bacterial contamination, endotoxin levels and the development of endometritis in postpartum cows with dystocia or retained placenta
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DOI：
10.1016/s0093-691x(00)00410-6
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发表时间：
2000-10-15
期刊：
影响因子：
2.8
通讯作者：
Lohuis, JACM
中科院分区：
文献类型：
--
作者：
Dohmen, MJW;Joop, K;Lohuis, JACM
一项研究旨在调查难产或胎盘保留的奶牛子宫内细菌污染、内毒素水平与子宫内膜炎发生之间的关系。 15头健康奶牛、31头胎盘滞留（RP）奶牛和13头难产奶牛在产后1或2天进行临床检查，同时采集子宫拭子进行细菌学检查。此外，还收集血浆和子宫恶露样本来测定脂多糖(LPS)和血浆IgG抗LPS浓度。随后，15 头 RP 奶牛和 6 头难产奶牛最初未经治疗，并在产后 2 周和 4 周时收集另一份子宫拭子。产犊后，RP 奶牛子宫恶露中的 LPS 水平显着高于难产奶牛和健康产后奶牛（平均分别为 0.10 和 0.26 EU/mL）（平均为 2.24 x 10(4) 内毒素单位 (EU)/mL）。然而，血浆 LPS 水平低于检测限（
A study was conducted to investigate the relationship between intra-uterine bacterial contamination, endotoxin levels and the development of endometritis in cows that experienced a dystocia or retained their placenta. Fifteen healthy cows, 31 cows with retained placenta (RP) and 13 cows that had dystocia were clinically examined 1 or 2 days after parturition when a uterine swab for bacteriological examination was taken. In addition, plasma and uterine lochia samples were collected to determine lipopolysaccharide (LPS) and the plasma IgG anti-LPS concentrations. Subsequently, 15 RP and 6 dystocia cows were initially left untreated and another uterine swab was collected at 2 and 4 wk postpartum. Immediately after calving, RP cows had significantly higher LPS levels in uterine lochia (average of 2.24 x 10(4) Endotoxin Units (EU)/mL) as compared to dystocia and healthy postpartum cows (average of 0.10 and 0.26 EU/mL, respectively). However, plasma LPS levels were below the detection limit (