Height and drinking status in relation to risk of anemia in rural adult healthy Japanese men: the Nagasaki Islands study
Height and drinking status in relation to risk of anemia in rural adult healthy Japanese men: the Nagasaki Islands study
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DOI：
10.3109/13685538.2014.942841
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发表时间：
2015-06-01
期刊：
影响因子：
2.6
通讯作者：
Maeda, Takahiro
中科院分区：
文献类型：
--
作者：
Shimizu, Yuji;Nakazato, Mio;Maeda, Takahiro
背景：一些研究报道身高与心血管疾病风险呈负相关，而与癌症风险呈正相关。另一方面，越来越多的证据表明，贫血反映出老年人的健康状况不佳，更容易受到不良结果的影响。此外，据报道，饮酒也与死亡率有关。方法：我们对1287名年龄在40-89岁之间的男性进行了一项横断面研究。结果：与经典的心血管危险因素无关，我们发现不饮酒者的身高与贫血之间存在显著的负相关关系，饮酒者的身高与贫血呈J型相关。非饮酒者贫血身高增加1 SD(标准差)的多变量优势比(OR)为0.59(0.45~0.77)。以身高第二四分位数(Q2)为参照组，身高最低四分位数(Q1)、身高四分位数(Q3)和身高四分位数(Q4)分别为2.68(0.9~7.96)(p=0.075)、2.73(0.92~8.08)和4.82(1.65~14.10)(p=0.004)。结论：身高与日本农村男性贫血有关，饮酒状况可能影响这些关联。
Background: Several studies have reported that height is inversely associated with risk of cardiovascular disease but positively associated with cancer risk. On the other hand, evidence has been accumulating that anemia reflects poor health and increased vulnerability to poor outcomes in older persons. Moreover, alcohol consumption has also been reported to be associated with mortality. However, no studies have reported on a possible association between height and risk of anemia in relation to drinking status.Methods: We conducted a cross-sectional study of 1287 men aged 40-89 years undergoing general health check-ups.Results: Independent from classic cardiovascular risk factors, we found a significant inverse association between height and anemia for non-drinkers and a J-shaped association for drinkers. The multivariable odds ratio (ORs) of an increment of 1 SD (standard deviation) in height (6.68 cm) for anemia for non-drinkers was 0.59 (0.45-0.77). For drinkers, with the second quartile of height (Q2) as the reference group, the multivariable OR of anemia was 2.68(0.90-7.96) (p = 0.075) for the lowest height quartile (Q1), 2.73(0.92-8.08) for the third quartile (Q3) and 4.82(1.65-14.10) for the highest quartile (Q4) (p=0.004).Conclusion: Height was found to be associated with anemia for rural Japanese men and drinking status is likely to affect those associations.