Association between Airflow Obstruction and the Metabolic Syndrome or Its Components in Japanese Men
Association between Airflow Obstruction and the Metabolic Syndrome or Its Components in Japanese Men
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DOI：
10.2169/internalmedicine.49.3882
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发表时间：
2010-01-01
影响因子：
1.2
通讯作者：
Katoh, Takahiko
中科院分区：
文献类型：
--
作者：
Funakoshi, Yayoi;Omori, Hisamitsu;Katoh, Takahiko
本横断面研究的目的是调查气流阻塞和代谢综合征（MS）或其组成部分在日本moment.Methods的研究包括7,189名男性受试者，年龄在45-88岁，谁接受了肺功能测试在体检之间的关联。肺功能测定诊断气流阻塞的标准为第一秒用力呼气量（FEV 1）/用力肺活量（FVC）<70%。结果本组患者气流阻塞的发生率为9.0%，MS的发生率为25.6%。在校正年龄、体重指数、吸烟和饮酒的logistic回归模型中，GOLD II-IV期气流阻塞受试者的MS风险高于肺功能正常受试者[比值比（OR），1.33; 95%置信区间（95%CI），1.01-1.76]。MS的组成部分，腰围（OR，1.76; 95% CI，1.24-2.50）和血压（OR，1.37;结论GOLD II-IV期气流阻塞可能与MS有关，日本男性的腰围和血压组成。
Background The aim of this cross-sectional study was to investigate the association between airflow obstruction and the metabolic syndrome (MS) or its components in Japanese men.Methods The study included 7,189 male subjects, aged 45-88 years, who underwent spirometric lung function tests at a medical check-up. The spirometric criteria for diagnosis of airflow obstruction were forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) < 70%. The severity of airflow obstruction was defined according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline.Results The prevalence of airflow obstruction was 9.0% and the frequency of MS was 25.6%. In logistic regression models adjusting for age, body mass index, smoking, and alcohol, the risk of MS was higher in subjects with airflow obstruction of GOLD stage II-IV compared to those with normal lung function [odds radio (OR), 1.33; 95% confidence interval (95% CI), 1.01-1.76)]. Of the MS components, waist circumference (OR, 1.76; 95% CI, 1.24-2.50) and blood pressure (OR, 1.37; 95% CI, 1.08-1.74) were associated with airflow obstruction of GOLD stage II-IV, after controlling for potential confounders.Conclusion Airflow obstruction of GOLD stage II-IV might be associated with MS, waist circumference and blood pressure components in Japanese men.