Corrigendum: HSP90 regulates temperature-dependent seedling growth in Arabidopsis by stabilizing the auxin co-receptor F-box protein TIR1.
Corrigendum: HSP90 regulates temperature-dependent seedling growth in Arabidopsis by stabilizing the auxin co-receptor F-box protein TIR1.
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DOI：
10.1038/ncomms11677
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发表时间：
2016-05-11
影响因子：
16.6
通讯作者：
Estelle M
中科院分区：
文献类型：
--
作者：
Wang R;Zhang Y;Kieffer M;Yu H;Kepinski S;Estelle M
最近的研究表明，环境温度的温和升高通过促进植物激素生长素的生物合成来刺激拟南芥幼苗的生长。然而，人们对这一过程中其他因素的作用知之甚少。在这份报告中，我们表明，温度升高促进快速积累的TIR1生长素共受体，一种依赖于分子伴侣HSP 90的效果。此外，我们表明，热休克蛋白90和辅助分子伴侣SGT1相互作用与TIR1，确认TIR1是一个热休克蛋白90的客户端。HSP90活性的抑制导致TIR 1的降解，有趣的是，在较低和较高温度下，生长素介导的生长过程的范围内的缺陷。我们的研究结果表明，热休克蛋白90和SGT1整合温度和生长素信号，以调节植物生长在一个不断变化的环境。
Recent studies have revealed that a mild increase in environmental temperature stimulates the growth ofArabidopsisseedlings by promoting biosynthesis of the plant hormone auxin. However, little is known about the role of other factors in this process. In this report, we show that increased temperature promotes rapid accumulation of the TIR1 auxin co-receptor, an effect that is dependent on the molecular chaperone HSP90. In addition, we show that HSP90 and the co-chaperone SGT1 each interact with TIR1, confirming that TIR1 is an HSP90 client. Inhibition of HSP90 activity results in degradation of TIR1 and interestingly, defects in a range of auxin-mediated growth processes at lower as well as higher temperatures. Our results indicate that HSP90 and SGT1 integrate temperature and auxin signalling in order to regulate plant growth in a changing environment.