Prevalence and correlates of septal delayed contrast enhancement in patients with. pulmonary hypertension
Prevalence and correlates of septal delayed contrast enhancement in patients with. pulmonary hypertension
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DOI：
10.1016/j.amjcard.2007.03.094
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发表时间：
2007-08-15
影响因子：
2.8
通讯作者：
Rajagopalan, Sanjay
中科院分区：
文献类型：
--
作者：
Sanz, Javier;Dellegrottaglie, Santo;Rajagopalan, Sanjay
使用心脏磁共振，心肌延迟对比增强（DCE）的存在已被描述在右心室插入点水平的肺动脉高压（PH）患者的室间隔。本研究的目的是调查这一发现的患病率、程度和相关性。在55例已知或疑似各种原因的PH患者中评价了间隔DCE。通过插入增强评分（范围0 - 4）目测估计DCE的程度，并量化为DCE质量。结果与电影磁共振和右侧心导管检查结果相关联。使用多变量分析研究了DCE的预测因素。42例患者（第1组）存在静息PH，13例患者（第2组）不存在。第1组中有41名患者（97%）发生DCE，第2组中有3名患者（23%）发生DCE（p < 0.0001）。第1组的DCE范围高于第2组（中位插入增强评分分别为3和0，中位DCE质量分别为8.7和0 g; P
Using cardiac magnetic resonance, the presence of myocardial delayed contrast enhancement (DCE) has been described in the ventricular septum at the level of the right ventricular insertion points in patients with pulmonary hypertension (PH). The aim of this study was to investigate the prevalence, extent, and correlates of this finding. Septal DCE was evaluated in 55 patients with known or suspected PH of various causes. The extent of DCE was estimated visually with an insertion enhancement score (range 0 to 4) and quantified as DCE mass. The results were correlated with cine magnetic resonance and right-sided cardiac catheterization. Predictors of DCE were investigated using multivariate analysis. PH at rest was present in 42 patients (group 1) and absent in 13 (group 2). DCE was noted in 41 patients (97%) in group 1 and 3 (23%) in group 2 (p < 0.0001). The extent of DCE was higher in group I than group 2 (median insertion enhancement score 3 vs 0, median DCE mass 8.7 vs 0 g, respectively; p