Flavan-4-ol Glycosides from the Rhizomes of Abacopteris penangiana.
Flavan-4-ol Glycosides from the Rhizomes of Abacopteris penangiana.
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DOI：
10.1021/np050191p
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发表时间：
2006-01
影响因子：
5.1
通讯作者：
Zhongxiang Zhao;J. Ruan;Jing Jin;Jian-hua Zou;Dao-nian Zhou;Wei Fang;Fa-Quan Zeng
中科院分区：
文献类型：
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作者：
Zhongxiang Zhao;J. Ruan;Jing Jin;Jian-hua Zou;Dao-nian Zhou;Wei Fang;Fa-Quan Zeng
从桔梗Abacopteris penangiana根茎的甲醇提取物中分离得到4个新的黄烷-4-醇苷类化合物abacopterins a- d(1-4)，以及2个已知化合物triphyllin a(5)和6,8-二甲基-7-羟基-4'-甲氧基花青素-5- o - β -d -glucopyranoside(6)。通过广泛的光谱分析和化学方法对它们的结构进行了鉴定。研究了1-5对HepG2人肝癌细胞的细胞毒活性。
Four new flavan-4-ol glycosides, abacopterins A-D (1-4), were isolated from a methanol extract of the rhizomes of Abacopteris penangiana, together with two known compounds, triphyllin A (5) and 6,8-dimethyl-7-hydroxy-4'-methoxyanthocyanidin-5-O-beta-D-glucopyranoside (6). Their structures were elucidated by extensive spectroscopic analysis and chemical methods. The cytotoxic activity of 1-5 against HepG2 human hepatoma cells was investigated.