Pulmonary fibrosis-an uncommon manifestation of anti-myeloperoxidase-positive systemic vasculitis?
Pulmonary fibrosis-an uncommon manifestation of anti-myeloperoxidase-positive systemic vasculitis?
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DOI：
10.1093/ndtplus/sfq050
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发表时间：
2010-08
期刊：
影响因子：
--
通讯作者：
Karim M
中科院分区：
文献类型：
--
作者：
Bhanji A;Karim M
小血管炎如显微镜下多血管炎和韦格纳肉芽肿病通常累及肾脏和肺部，肺泡出血是肺部受累的最常见表现。在这里，我们描述了一个病人谁开发的急性肾功能衰竭和肺出血阳性自身抗体抗髓过氧化物酶1年后，诊断为普通间质性肺炎，我们讨论了肺纤维化和抗髓过氧化物酶阳性血管炎的罕见关联。
Small vessel vasculitides such as microscopic polyangiitis and Wegener’s granulomatosis commonly involve the kidney and lung, with alveolar haemorrhage being the commonest manifestation of pulmonary involvement. Here we describe a patient who developed acute renal failure and pulmonary haemorrhage with positive autoantibodies against myeloperoxidase 1 year after a diagnosis of usual interstitial pneumonia had been made and we discuss the uncommon association of pulmonary fibrosis and anti-myeloperoxidase positive vasculitis.