Spatial epidemiology of networked metapopulation: an overview
Spatial epidemiology of networked metapopulation: an overview
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DOI：
10.1101/003889
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发表时间：
2014-06
期刊：
影响因子：
--
通讯作者：
Lin Wang;Xiang Li
中科院分区：
文献类型：
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作者：
Lin Wang;Xiang Li
新出现的疾病是一种新的传染性病原体引起的传染病，这种病原体要么是第一次出现，要么已经存在于人群中，有能力在发病率和地理范围上迅速增加。适应人类免疫系统，新出现的疾病可能会引发大规模的流行性传播，如SARS的跨国传播，A（H1N1）的全球爆发，以及最近可能入侵的禽流感A（H7N9）。网络集合种群的空间流行病学模型考虑了空间分布因素，为研究新出现疾病传播的动力学机制提供了一个有价值的建模框架。本文综述了集合种群空间动力学研究的最新进展，讨论了验证网络集合种群有效性的经验和理论研究成果，以及网络集合种群在疾病干预策略有效性评价中的应用。
An emerging disease is one infectious epidemic caused by a newly transmissible pathogen, which has either appeared for the first time or already existed in human populations, having the capacity to increase rapidly in incidence as well as geographic range. Adapting to human immune system, emerging diseases may trigger large-scale pandemic spreading, such as the transnational spreading of SARS, the global outbreak of A(H1N1), and the recent potential invasion of avian influenza A(H7N9). To study the dynamics mediating the transmission of emerging diseases, spatial epidemiology of networked metapopulation provides a valuable modeling framework, which takes spatially distributed factors into consideration. This review elaborates the latest progresses on the spatial metapopulation dynamics, discusses empirical and theoretical findings that verify the validity of networked metapopulations, and the sketches application in evaluating the effectiveness of disease intervention strategies as well.