Blood toluene as a biological index of environmental toluene exposure in the “normal” population and in occupationally exposed workers immediately after exposure and 16 hours later

Blood toluene as a biological index of environmental toluene exposure in the “normal” population and in occupationally exposed workers immediately after exposure and 16 hours later
复制标题

血液甲苯作为“正常”人群和职业暴露工人中甲苯暴露后立即和 16 小时后环境甲苯暴露的生物指标

DOI:
10.1007/bf00383150
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发表时间:
1995
影响因子:
3
通讯作者:
L. Perbellini
L. Perbellini
中科院分区:
医学3区
文献类型:
--
作者:
F. Brugnone;M. Gobbi;K. Ayyad;C. Giuliari;M. Cerpelloni;L. Perbellini

文献摘要

被引文献

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在一组100名工人职业暴露于平均8小时环境甲苯浓度为128 μg/l(34 ppm),并在一组269名“正常”的主题没有职业暴露于甲苯的血液甲苯进行了测量。在轮班结束时和第二天早上,16小时后,工人的平均血液甲苯分别为457和38 μg/l。正常受试者的血液甲苯水平为1.1 μg/l。根据血液甲苯与职业接触之间的高度显著相关性,可以计算出,环境甲苯接触量为188和377 μg/l(50和100 ppm)时,轮班结束时血液甲苯水平分别为690和1390 μg/l。第二天早上相应的血液甲苯水平分别为50和100 μ/l。
Blood toluene was measured in a group of 100 workers occupationally exposed to a mean 8-h environmental toluene concentration of 128 μg/l (34 ppm), and in a group of 269 “normal” subjects without occupational exposure to toluene. The mean blood toluene of the workers at the end of the shift and the following morning, after 16 h, was 457 and 38 μg/l, respectively. The normal subjects had a blood toluene level of 1.1 μg/l. On the basis of the highly significant correlation between blood toluene and occupational exposure, it can be calculated that environmental toluene exposure of 188 and 377 μg/l (50 and 100 ppm) gives end-of-shift blood toluene levels of 690 and 1390 μg/l, respectively. The corresponding blood toluene levels on the following morning are 50 and 100 μ/l, respectively.