Testing for genetic trade-offs between early- and late-life reproduction in a wild red deer population
Testing for genetic trade-offs between early- and late-life reproduction in a wild red deer population
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DOI：
10.1098/rspb.2007.0986
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发表时间：
2008-03-22
影响因子：
4.7
通讯作者：
Kruuk, Loeske E. B.
中科院分区：
文献类型：
--
作者：
Nussey, Daniel H.;Wilson, Alastair J.;Kruuk, Loeske E. B.
衰老的拮抗多效性（AP）理论预测了基于基因的早期生殖投资与后期生存和表现之间的权衡。以实验室为基础的研究表明，这种基因权衡是存在的，但目前对它们在自然种群中的普遍程度知之甚少。我们使用随机回归“动物模型”技术来测试苏格兰朗姆岛野生马鹿种群（Cervus elaphus）早期繁殖力（ELF）和晚年母鹿表现之间权衡的遗传基础。在这一人群中，在关键的母亲表现指标（后代出生体重）和ELF中，衰老率都存在显著的遗传变异。我们发现了一些证据，证明后代出生体重的衰老速度与ELF之间存在负遗传协方差，也存在负环境协方差。我们的研究结果为野生种群衰老的AP理论提供了罕见的支持。
The antagonistic pleiotropy (AP) theory of ageing predicts genetically based trade-offs between investment in reproduction in early life and survival and performance in later life. Laboratory-based research has shown that such genetic trade-offs exist, but little is currently known about their prevalence in natural populations. We used random regression `animal model' techniques to test the genetic basis of trade-offs between early-life fecundity ( ELF) and maternal performance in late life in a wild population of red deer (Cervus elaphus) on the Isle of Rum, Scotland. Significant genetic variation for both ageing rates in a key maternal performance measure ( offspring birth weight) and ELF was present in this population. We found some evidence for a negative genetic covariance between the rate of ageing in offspring birth weight and ELF, and also for a negative environmental covariance. Our results suggest rare support for the AP theory of ageing from a wild population.